Translational and Experimental Research in Trauma Surgery

In 2016, the WHO reported that in Europe alone, around half a million people die every year as a result of violence and traumatic injuries. This makes trauma the leading cause of death worldwide for people under the age of 45.
A severe trauma is followed by a systemic immune response of varying degrees. If the immune system is overwhelmed by the severity of the injury, a life-threatening dysfunction of the immune system and blood coagulation can occur. This compromise of the body's defences can lead to sepsis. Sepsis is a failure of one or more organ systems caused by an infection and represents a life-threatening medical emergency.
Our focus is on researching the post-traumatic molecular and cellular mechanisms that lead to a dysfunctional immune response of the innate and acquired immune system. In order to improve the care of severely injured patients, we are researching these in preclinical and clinical studies. Our aim is to optimise diagnostics and treatment strategies in trauma and sepsis.
The close spatial and personal contact between the team at the Department of Trauma Surgery and the scientists at the trauma laboratory ideally facilitates the transfer of clinical questions to the laboratories and vice versa, thus enabling translational research.
National and international co-operation with basic scientists and clinicians as well as networking within the University of Ulm, especially within the framework of the SFB1149, are important resources for our research.

Management

  • Profilbild von Prof. Dr. phil. nat. Borna Relja

    Prof. Dr. phil. nat. Borna Relja

    Leitung Unfallchirurgische Translationale und Experimentelle Forschung

Working group leaders

  • Profilbild von Dr. med. sci. Christian Bergmann

    Dr. med. sci. Christian Bergmann

    Assistenzarzt, Arbeitsgruppenleiter Trauma und Sepsis, Clinician Scientist, Stellvertretender Leiter Unfallchirurgische Translationale und Experimentelle Forschung

  • Profilbild von Dr. med. Nils Becker

    Dr. med. Nils Becker

    Clinical Scientist

  • Profilbild von Dr. rer. nat. Jasmin Bülow

    Dr. rer. nat. Jasmin Bülow

    Postdoc

  • Profilbild von Dr. sc. hum. Helen Rinderknecht

    Dr. sc. hum. Helen Rinderknecht

    Postdoc

  • Profilbild von Dr. rer. nat. Alessa Wagner

    Dr. rer. nat. Alessa Wagner

    Postdoc

Medical doctoral students

Technical employees

  • Profilbild von  Bettina Herde

    Bettina Herde

    MTLA

  • Profilbild von M.Sc. Chahinaz Rawas

    M.Sc. Chahinaz Rawas

    Technische Assistentin

  • Profilbild von  Patricia Scheible

    Patricia Scheible

    BTA

New job advertisements

Medical doctoral students wanted
Research assistants wanted

Applications with CV and letter of motivation can be sent by email to the following address:

borna.relja@uniklinik-ulm.de,christian.bergmann@uniklinik-ulm.de

Video of the medical faculty

 

 

Trauma Lab (English)

In 2016, WHO reported that approximately half a million people die each year in Europe alone as a result of exposure to violence and traumatic injury. Trauma is the leading cause of death worldwide for people under the age of 45.

Following severe trauma, a systemic immune response of varying magnitude occurs. If the immune system is overwhelmed by the severity of the injury, life-threatening immune and blood clotting dysfunction can occur. As part of this compromise of the body's defences, sepsis can occur. Sepsis is a failure of one or more organ systems caused by an infection and is a life-threatening medical emergency.

Our focus is to understand the post-traumatic molecular and cellular mechanisms that lead to a dysfunctional immune response of the innate and acquired immune system. In order to improve the care of severely injured patients, we study them in preclinical and clinical trials. In doing so, our goal is to optimise diagnostics and therapeutic strategies in trauma and sepsis.

The close spatial and personal contact between the team of the Department of Trauma Surgery and the scientists of the trauma laboratory ideally enables the transfer of clinical questions to the laboratories and vice versa, thus facilitating translational research.

National and international collaborations with basic scientists and clinicians as well as networking within the University of Ulm, especially within the SFB1149, represent important resources for our research.

video of the medical faculty (English)

 

 

Impressions from research