The Chair of Medical Radiation Physics combines medical imaging and molecular radiotherapy as fundamental components of innovative concepts in precision medicine(theranostics). The research work therefore focuses on the optimisation of individual diagnostics and therapy with a particular emphasis on the translation of theoretical methods into clinical routine.

The research professorship for Medical Radiation Physics focuses on

  • Optimisation of molecular radiotherapy with optimal utilisation of prior knowledge from various sources such as
    - from individual functional and anatomical imaging
    - from prior knowledge of the relevant patient population and
    - from general prior knowledge regarding anatomical, (patho)physiological and (radio)biological conditions.
  • Carrying out in silico (clinical) studies to improve the therapy planning of molecular radiotherapy
  • Development and implementation of new physiologically based pharmacokinetic (PBPK) and pharmacodynamic (PD) models and translation from research to the clinic
  • Improvement of evaluation methods for functional imaging

 

 

Profilbild von Prof. Dr. rer. nat. Gerhard Glatting

Prof. Dr. rer. nat. Gerhard Glatting

Dipl.-Phys., Medizinphysik-Experte (MPE)

Publications

The following link provides an overview of the publications of the respective person.

Univ.-Prof. Dr Gerhard Glatting (Dipl.-Phys.)

Dr Elham Yousefzadeh-Nowshahr (MPE)

Vacancies

Master's theses/Bachelor's theses

We offer interdisciplinary topics focussing on biology, radiochemistry, physics, medical physics, image processing, etc.
Examples of master's thesis topics in recent years include

  • Calibration and optimisation of the measurement protocol for 177Luon the Siemens Symbia T2 SPECT/CT system
  • Calibration and optimisation of the measurement protocol for the quantitative measurement of 90Yusing PET/CT
  • Optimisation of dosimetry for radioiodine therapy in benign thyroid diseases


If you are interested in writing a Master's or Bachelor's thesis, please send your application to Prof. Dr Gerhard Glatting.

Scholarship applications

We are happy to support individual scholarship applications within the framework of the Marie Skłodowska-Curie Actions (MSCA) and the German Academic Exchange Service.
If you are interested, please also contact Prof Dr Gerhard Glatting.

Prices

Congratulations to Dr Deni Hardiansyah for winning the 1st Tomio Inoue Award at the 16th Asian and Oceanian Congress of Nuclear Medicine and Biology (AOCNMB). The work presented is based on a collaboration between the Ulm Medical Radiation Physics Group, the Department of Medical Physics and Biophysics at Universitas Indonesia and the Medical Physics Group at the Department of Nuclear Medicine at Freiburg University Hospital.

In the study entitled "Single-time-point kidneys and tumor absorbed dose calculation during [177Lu]Lu-PSMA-617 therapy using non-linear mixed-effects modeling", it was shown that a single SPECT/CT measurement 2 days after injection can predict the absorbed dose of kidneys and tumours during[177Lu]Lu-PSMA-617 therapy. The newly developed "STP-NLME" approach outperforms the commonly used simple STP method.

The Tomio Inoue Award is an honour given to scientists and researchers in the field of nuclear medicine who have made a significant contribution to the field. The award is named after Tomio Inoue, a leading figure in the field of nuclear medicine and biology, who is recognised for his scientific contributions to the development of medical imaging technology and nuclear medicine therapies.

The cooperation between the Ulm Medical Radiation Physics Group, the Department of Medical Physics and Biophysics at Universitas Indonesia and the Medical Physics Group at the Department of Nuclear Medicine at the University Hospital of Würzburg was honoured with the "International Best Abstract Award for Indonesia" for its contribution to the annual meeting of the American Society of Nuclear Medicine and Molecular Imaging (SNMMI).

The developed method optimises the accuracy and thus the reproducibility between different examiners. The resulting simplified dosimetry with only one measurement after 120 hours using the NLME method shows that it is acceptable and provides accurate values for thyroid therapy with 131I.

A Population-Based Model Selection in Single Time Point Dosimetry Using Non-Linear Mixed Effects Modelling for Benign Thyroid Disease. Deni Hardiansyah, Ade Riana, Heribert Hänscheid, Michael Lassmann and Gerhard Glatting Journal of Nuclear Medicine June 2024, 65 (supplement 2) 242061

The cooperation between the Ulm Group for Medical Radiation Physics and the Department of Medical Physics and Biophysics at Universitas Indonesia was honoured with the "International Best Abstract Award for Indonesia" for its contribution to the annual meeting of the American Society for Nuclear Medicine and Molecular Imaging (SNMMI).

In molecular radiotherapy, an individual determination of time-integrated activities is required. The aim of this study was to develop an optimised, more reproducible method that combines non-linear mixed-effects modelling with population-based model selection for accurate determination of time-integrated activities. The technique was demonstrated using the example of renal dosimetry in 177Lu-PSMA therapy.

D. Hardiansyah, A. Riana, M. Eiber, A. J. Beer, G. Glatting, " Improving the accuracy of the time-integrated activity using non-linear mixed-effects modelling and population-based model selection in molecular radiotherapy," J Nuc Med 64, P519 (2023).

The cooperation between the Ulm Medical Radiation Physics Group and the Department of Medical Physics and Biophysics at Universitas Indonesia was honoured with the "International Best Abstract Award for Indonesia" for its contribution to the annual meeting of the American Society of Nuclear Medicine and Molecular Imaging (SNMMI).

The award-winning paper explores ways to individualise nuclear medicine therapy using prior knowledge of the patient population.

D. Hardiansyah, A. Riana, P. Kletting, N. Zaid, A. Beer, G. Glatting, "Model Selection Based on Population Fitting at an Example of 177Lu-PSMAKinetics in Kidneys with a Low Number of Data," J Nuc Med 62, 1435-1435 (2021).

Calculating the optimal tumour therapy

Award: Ulm medical physicist Dr Peter Kletting receives the Science Prize of the German Society for Medical Physics

The German Society for Medical Physics (DGMP) has honoured Dr biol. hum. Peter Kletting, medical physicist at the Department of Nuclear Medicine at Ulm University Hospital, with the Science Award 2020 for his research into the targeted irradiation of tumour tissue with radioactively labelled peptides.

You can read a detailed description of the research work here.

Nusrat Begum, PhD student in the Department of Nuclear Medicine, was honoured with the Alavi Mandell Prize 2019

Nusrat Jihan Begum, MSc, PhD student in the Department of Nuclear Medicine at Ulm University Hospital, has been awarded the American Alavi Mandell Prize for her publication in The Journal of Nuclear Medicine (JNM, Impact Factor 7.4 (2017)). The prize was awarded for her publication entitled "The effect of total tumour volume on the biologically effective dose of tumour and kidney for 177Lu-labelledPSMA peptides".

("The effect of total tumor volume on the biologically effective dose of tumor and kidneys for 177Lu-labelled PSMA peptides").

Publication by Dr Peter Kletting, Department of Nuclear Medicine at Ulm University Hospital, was honoured by the German Society of Nuclear Medicine (DGN)

For his achievements in the field of nuclear medicine therapy, Dr biol. hum. Peter Kletting, a member of staff at the Department of Nuclear Medicine | Medical Radiation Physics at Ulm University Hospital , has been awarded this year's German Society of Nuclear Medicine (DGN) sponsorship prize for his achievements in the field of nuclear medicine therapy. The award is endowed with 3,000 euros. The prize is awarded to scientific publications that make an outstanding contribution to the establishment or optimisation of nuclear medicine therapies. Further information can be found in the press release.

Dr biol. hum. Peter Kletting (Ulm) has received one of the 3 Behnken-Berger Prizes 2017 for the development of a method to improve the therapeutic index for radioligand therapy. (Publication)

The award ceremony took place during the joint annual conference of the Biomedical Engineering and the three-country conference of Medical Physics on 11 September 2017 in Dresden.

Dr Peter Kletting's award-winning work describes a method that can be used to improve the therapeutic index for radioligand therapy.

With the help of the physiologically based pharmacokinetic model developed by Dr Kletting and the simulation algorithm, the combination of activity and amount of peptide used can be determined individually for each patient, which leads to the optimal ratio of biologically effective dose in the tumour to organs at risk. This increases the effectiveness of the therapy while the radiation exposure remains the same, or the radiation exposure of the organs at risk can be minimised for a given effect. The method developed can be transferred to other substances and is therefore extremely relevant for current and future therapy concepts. They therefore represent an important step in minimising the radiation exposure of patients. This outstanding work is closely related to the work previously published by Dr Kletting in the field of therapeutic use of ionising radiation.

The Ulm and Mannheim Medical Radiation Physics Group were honoured with the "International Best Abstract Award" for their contribution to the annual meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) in Denver, Colorado.

The award-winning paper examines ways to individualise nuclear medicine therapy. The results of the investigations have already been published.

By: Petra Schultze

Ulm medical physicists Dr Peter Kletting and Prof Dr Gerhard Glatting from the University Department of Nuclear Medicine have been awarded the prize for the best scientific article in the Journal of Medical Physics 2015.

The German Society of Nuclear Medicine honours young scientist Peter Kletting from the Department of Nuclear Medicine with the Covidien Nuclear Medicine Award. [more]

By: Jörg Portius

Medical physicist Prof. Dr Glatting is honoured for his research by the German Society for Medical Physics on 13 September

The German Society for Medical Phys ics (DGMP) is honouring Ulm medical physicist Prof. Dr. Gerhard Glatting for his research into the targeted irradiation of tumour tissue with radioactively labelled antibodies in cancer patients. [more]

Contact us

Phone 0731 500 - 61340

Fax 0731 500 - 61302

Address
Ulm University Hospital
Department of Nuclear Medicine
Chair of Medical Radiation Physics
Albert-Einstein-Allee 23
89081 Ulm

You can reach us by phone:
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