The Clinic for Dental Prosthetics focuses on biomaterial research in clinical studies (a list of these studies and information on possible participation as a test subject can be found at this link). Studies are currently being conducted in Ulm and at other locations on

  • High-performance ceramics (survival of different materials and constructions on teeth and implants),
  • hybrid ceramics,
  • soft tissue management on teeth and implants,
  • molecular biological analyses of inflammation markers,
  • the impression precision that can be achieved,
  • therapy alternatives for deeply damaged teeth,
  • combined tooth-implant-supported bridges,
  • pre-implantological bone preservation,
  • the precision of three-dimensional implant planning,
  • total mandibular prostheses stabilised by a single implant
  • the use of a sleeveless surgical guide for navigated implant placement and
  • reverse-fix technology for the non-destructive removal and reattachment of dental restorations

are carried out.

Eight members of the department are currently trained as clinical investigators.
Four dentists are also qualified for studies in accordance with the German Medical Devices Act (MPG).

Various testing machines and equipment for dynamic thermal alternating loading (chewing simulator, developed in-house by the department and the company Zwick/Roell, Einsingen), a universal testing machine and mechanical and non-contact optical digitisation technology are available for in-vitro examinations. In addition to three-dimensional analyses using CAD software, voxel-based data can also be processed. In current experiments, high-performance ceramic abutments (implant abutment components) and implants, osteosynthesis plates for the lower jaw (titanium, hand-bent or laser-sintered) or the primary stability of implants are tested in preparations.

In teaching research, new teaching and learning materials are designed and implemented using modern computer-aided processes and software development to improve pre-clinical and clinical dental training.

 

Under this link we report on the results of CAD/CAM research and provide information on CAD/CAM technology.

 

All articles on RaSDA - 15-year results of the multicentre clinical study on the shortened dental arch (Radomized shortened dental arch study) are available on Quintessence-Verlags GmbH

 

Rentschler, Maria/Rudolph, Heike/Luthardt, Ralph - Comparison of the two treatment alternatives with the main outcome "tooth loss" - DZZ 4/2024

Ploner, Evelyn/Rudolph, Heike/Luthardt, Ralph- Periodontological aspects - DZZ 4/2024

Bauder, Charlotte/Rudolph, Heike/Luthardt, Ralph- Prosthetic aftercare expenditure -DZZ 4/2024

 

All articles also on PubMed available

 

1
Associations among Primary Stability, Histomorphometric Findings, and Bone Density: A Prospective Randomised Study after Alveolar Ridge Preservation with a Collagen Cone.
Schnutenhaus S, Götz W, Dreyhaupt J, Rudolph H, Luthardt RG, Edelmann C. Dent J (Basel). 2020 Oct 2;8(4):112. doi: 10.3390/dj8040112. PMID: 33023224 Free PMC article.
2
Alveolar ridge preservation with a collagen cone: Histological, histochemical, and immunohistochemical results of a randomised controlled clinical trial.
Schnutenhaus S, Edelmann C, Dreyhaupt J, Rudolph H, Luthardt RG, Goetz W. Clin Exp Dent Res. 2020 Jun;6(3):345-355. doi: 10.1002/cre2.279. Epub 2020 Jan 22. PMID: 31967736 Free PMC article.
3
Reliability of light microscopy and a computer-assisted replica measurement technique for evaluating the fit of dental copings.
Rudolph H, Ostertag S, Ostertag M, Walter MH, Luthardt RG, Kuhn K. J Appl Oral Sci. 2018 Feb 1;26:e20160590. doi: 10.1590/1678-7757-2016-0590. PMID: 29412364 Free PMC article.
4
Alveolar ridge preservation with a collagen material: a randomised controlled trial.
Schnutenhaus S, Doering I, Dreyhaupt J, Rudolph H, Luthardt RG. J Periodontal Implant Sci. 2018 Aug 31;48(4):236-250. doi: 10.5051/jpis.2018.48.4.236. eCollection 2018 Aug. PMID: 30202607 Free PMC article.
5
Accuracy of the match between cone beam computed tomography and model scan data in template-guided implant planning: A prospective controlled clinical study.
Schnutenhaus S, Gröller S, Luthardt RG, Rudolph H. Clin Implant Dent Relat Res. 2018 Aug;20(4):541-549. doi: 10.1111/cid.12614. Epub 2018 Apr 25. PMID: 29691987
6
Characterisation of the transmission behaviour of dental filling materials and cements for the diode lasers' and the Nd:YAG laser's wavelengths.
Diebolder R, Schmid CU, Luthardt RG, Rudolph H, Kuhn K. Lasers Surg Med. 2019 Sep;51(7):653-663. doi: 10.1002/lsm.23081. Epub 2019 Mar 7. PMID: 30843244
7
Alveolar ridge preservation and primary stability as influencing factors on the transfer accuracy of static guided implant placement: a prospective clinical trial.
Schnutenhaus S, Brunken L, Edelmann C, Dreyhaupt J, Rudolph H, Luthardt RG. BMC Oral Health. 2020 Jun 29;20(1):178. doi: 10.1186/s12903-020-01155-x. PMID: 32600405 Free PMC article. Clinical Trial.
8
Reproducibility of CBCT image analysis: a clinical study on intrapersonal and interpersonal errors in bone structure determination.
Schnutenhaus S, Graf M, Doering I, Luthardt RG, Rudolph H. Oral Radiol. 2019 May;35(2):152-158. doi: 10.1007/s11282-018-0340-1. Epub 2018 Jul 27. PMID: 30484198
9
Retrospective study to determine the accuracy of template-guided implant placement using a novel nonradiologic evaluation method.
Schnutenhaus S, Edelmann C, Rudolph H, Luthardt RG. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Apr;121(4):e72-9. doi: 10.1016/j.oooo.2015.12.012. Epub 2016 Jan 4. PMID: 26972545
10
Biological complications of removable dental prostheses in the moderately reduced dentition: a systematic literature review.
Moldovan O, Rudolph H, Luthardt RG. Clin Oral Investig. 2018 Sep;22(7):2439-2461. doi: 10.1007/s00784-018-2522-y. Epub 2018 Jun 29. PMID: 29959596
11
Survival and Complications of Single Dental Implants in the Edentulous Mandible Following Immediate or Delayed Loading: A Randomised Controlled Clinical Trial.
Kern M, Att W, Fritzer E, Kappel S, Luthardt RG, Mundt T, Reissmann DR, Rädel M, Stiesch M, Wolfart S, Passia N. J Dent Res. 2018 Feb;97(2):163-170. doi: 10.1177/0022034517736063. Epub 2017 Oct 18. PMID: 29045800 Free PMC article. Clinical Trial.
12
Clinical performance of removable dental prostheses in the moderately reduced dentition: a systematic literature review.
Moldovan O, Rudolph H, Luthardt RG. Clin Oral Investig. 2016 Sep;20(7):1435-47. doi: 10.1007/s00784-016-1873-5. Epub 2016 Jun 9. PMID: 27283325 Review.
13
Dimensional Changes of the Soft Tissue after Alveolar Ridge Preservation with a Collagen Material. A Clinical Randomised Trial.
Schnutenhaus S, Martin T, Dreyhaupt J, Rudolph H, Luthardt RG. Open Dent J. 2018 May 30;12:389-399. doi: 10.2174/1874210601812010389. eCollection 2018. PMID: 29988229 Free PMC article.
14
3D accuracy of implant positions in template-guided implant placement as a function of the remaining teeth and the surgical procedure: a retrospective study.
Schnutenhaus S, Edelmann C, Rudolph H, Dreyhaupt J, Luthardt RG. Clin Oral Investig. 2018 Jul;22(6):2363-2372. doi: 10.1007/s00784-018-2339-8. Epub 2018 Jan 22. PMID: 29356920
The data of the planned implant positions were overlaid with the actual clinical implant positions, followed by measurements of the 3D deviations in terms of coronal (x(c)) and apical distance, height (x(h)), and angulation (ang) and statistical analysis. RESULTS: The mean ...
15
Periodontal health in shortened dental arches: A 10-year RCT.
Walter MH, Dreyhaupt J, Mundt T, Kohal R, Kern M, Rauch A, Nothdurft F, Hartmann S, Böning K, Boldt J, Stark H, Edelhoff D, Wöstmann B, Luthardt RG, Hannak W, Wolfart S, Heydecke G, Jahn F, Pospiech P, Marré B. J Prosthodont Res. 2020 Oct;64(4):498-505. doi: 10.1016/j.jpor.2020.01.005. Epub 2020 Feb 13. PMID: 32063531 Clinical Trial.
16
The S-S Bridge: A Mixed Experimental-Computational Estimation of the Equilibrium Structure of Diphenyl Disulfide.
Demaison J, Vogt N, Saragi RT, Juanes M, Rudolph HD, Lesarri A. Chemphyschem. 2019 Feb 4;20(3):366-373. doi: 10.1002/cphc.201800973. Epub 2018 Dec 21. PMID: 30476349
The disulfide bridge (-S-S-) is an important structural motif in organic and protein chemistry, but only a few accurate equilibrium structures are documented. We report the results of supersonic-jet microwave spectroscopy experiments on the rotational spectra of dip ...
17
5-year randomized multicenter clinical trial on single dental implants placed in the midline of the edentulous mandible.
Kern M, Behrendt C, Fritzer E, Kohal RJ, Luthardt RG, Maltzahn NFV, Rädel M, Reissmann DR, Schwindling FS, Wolfart S, Passia N. Clin Oral Implants Res. 2021 Feb;32(2):212-221. doi: 10.1111/clr.13692. Epub 2020 Dec 26. PMID: 33258136 Clinical Trial.
18
Stabilising mandibular complete dentures by a single midline implant-influence on quality of life: 2-year results from a randomized clinical trial comparing different loading protocols.
Abou-Ayash S, von Maltzahn N, Passia N, Freitag-Wolf S, Reissmann DR, Luthardt RG, Mundt T, Raedel M, Rammelsberg P, Wolfart S, Kern M. Clin Oral Investig. 2020 Feb;24(2):927-935. doi: 10.1007/s00784-019-02969-y. Epub 2019 Jun 27. PMID: 31250193 Clinical Trial.
19
Pain and discomfort following immediate and delayed loading by overdentures in the single mandibular implant study (SMIS).
Mundt T, Passia N, Att W, Heydecke G, Freitag-Wolf S, Luthardt RG, Kappel S, Konstantinidis IK, Stiesch M, Wolfart S, Kern M. Clin Oral Investig. 2017 Mar;21(2):635-642. doi: 10.1007/s00784-016-1930-0. Epub 2016 Aug 12. PMID: 27519188 Clinical Trial.
20
Impact of shortened dental arch on oral health-related quality of life over a period of 10 years - A randomised controlled trial.
Reissmann DR, Wolfart S, John MT, Marré B, Walter M, Kern M, Kohal R, Nothdurft F, Stark H, Schierz O, Wöstmann B, Hannak W, Mundt T, Pospiech P, Boldt J, Edelhoff D, Busche E, Jahn F, Luthardt RG, Hartmann S, Heydecke G. J Dent. 2019 Jan;80:55-62. doi: 10.1016/j.jdent.2018.10.006. Epub 2018 Oct 21. PMID: 30355509 Clinical Trial.
21
How flexible is the disulfide linker? A combined rotational-computational investigation of diallyl disulfide.
Demaison J , Vogt N , Saragi RT , Juanes M , Rudolph HD , Lesarri A . Phys Chem Chem Phys. 2019 Sep 18;21(36):19732-19736. doi: 10.1039/c9cp02508a. PMID: 31192318
22
Accuracy of Dynamic Computer-Assisted Implant Placement: A Systematic Review and Meta-Analysis of Clinical and In Vitro Studies.
Schnutenhaus S, Edelmann C, Knipper A, Luthardt RG. J Clin Med. 2021 Feb 11;10(4):704. doi: 10.3390/jcm10040704. PMID: 33670136 Free PMC article. Review.
23
Prosthetic rehabilitation of a patient with cleidocranial dysplasia using dental implants-a clinical report.
Schnutenhaus S, Götz W, Luthardt RG. Int J Implant Dent. 2021 Jan 22;7(1):5. doi: 10.1186/s40729-020-00287-7. PMID: 33479858 Free PMC article.
24
The randomised shortened dental arch study: influence of two different treatments on interdental spacing over 5 years.
Kern JS, Wolfart S, Hilgers RD, Marré B, Scheller H, Strub J, Böning K, Hannak W, Luthardt RG, Heydecke G, Huppertz J, Pospiech P, Wöstmann B, Stark H, Mundt T, Jahn F, Kern M, Edelhoff D, Walter MH. Clin Oral Investig. 2017 Jul;21(6):1945-1951. doi: 10.1007/s00784-016-1981-2. Epub 2016 Oct 26. PMID: 27785586 Clinical Trial.
25
Axial-equatorial isomerism and semi-experimental equilibrium structures of fluorocyclohexane.
Juanes M, Vogt N, Demaison J, León I, Lesarri A, Rudolph HD. Phys Chem Chem Phys. 2017 Nov 8;19(43):29162-29169. doi: 10.1039/c7cp06135h. PMID: 29086779
26
Rehabilitation of shortened dental arches: A fifteen-year randomised trial.
Walter MH, Marré B, Dreyhaupt J, Heydecke G, Rauch A, Mundt T, Hannak W, Kohal RJ, Kern M, Nothdurft F, Hartmann S, Böning K, Boldt J, Stark H, Edelhoff D, Wöstmann B, Wolfart S, Jahn F, Luthardt RG. J Oral Rehabil. 2021 Mar 13. doi: 10.1111/joor.13167. Online ahead of print. PMID: 33713361
27
Semiexperimental and mass-dependent structures by the mixed regression method: Accurate equilibrium structure and failure of the Kraitchman method for ethynylcyclohexane.
Vogt N, Demaison J, Rudolph HD, Juanes M, Fernández J, Lesarri A. J Chem Phys. 2018 Feb 14;148(6):064306. doi: 10.1063/1.5018053. PMID: 29448780
28
Fourier Transform Microwave Spectrum of Propene-3-d1 (CH2═CHCH2D), Quadrupole Coupling Constants of Deuterium, and a Semiexperimental Equilibrium Structure of Propene.
Demaison J, Craig NC, Gurusinghe R, Tubergen MJ, Rudolph HD, Coudert LH, Szalay PG, Császár AG. J Phys Chem A. 2017 Apr 27;121(16):3155-3166. doi: 10.1021/acs.jpca.7b01470. Epub 2017 Apr 18. PMID: 28368600
Transitions were assigned for the two conformers, one with the D atom in the symmetry plane (S) and the other with the D atom out of the plane (A). The energy difference between the two conformers was calculated to be 6.5 cm(-1), the S conformer having lower energy. ...
29
The equilibrium molecular structures of 2-deoxyribose and fructose by the semi-experimental mixed estimation method and coupled-cluster computations.
Vogt N, Demaison J, Cocinero EJ, Écija P, Lesarri A, Rudolph HD, Vogt J. Phys Chem Chem Phys. 2016 Jun 21;18(23):15555-63. doi: 10.1039/c6cp01842e. Epub 2016 May 23. PMID: 27212641