Contact: Prof. V. Rasche ✉

Investigation of the biodistribution of new pharmaceutical compounds is of paramount importance for e.g. assessment of the efficiency of specific substrate targeting. Early investigation of the properties of new contrast agents (CA) or labelled compounds highly depends on the availability of suited in vivo models. The usage of chick embryonic models with xenotransplanted tumors on the chorioallantoic membrane (CAM) has shown to be an efficient alternative to murine models. We use in ovo tumor models to investigate the biodistribution of MR labelled compounds.