Image-Guided Interventions


Head: Dr. biol. hum. Ina Vernikouskaya ✉

Transvascular procedures are commonly performed under x-ray (XR) fluoroscopy guidance. Providing high temporal and spatial resolution, XR lacks anatomical information. Multimodal intra-procedural three-dimensional (3D) image fusion (IF) can augment the limited information available from XR with relevant anatomic soft-tissue structures. Visualization of anatomical information is achieved by projecting organ shape models derived from e.g. high-fidelity pre-interventional computed tomography angiography (CTA) or magnetic resonance imaging (MRI) data on the live fluoroscopy image.

Objectives:

  • To develop a platform for integration of pre-interventional anatomical and functional data with realtime X-ray fluoroscopy data.
  • To provide a three-dimensional navigation tool for reproducible 3D positioning of the working catheter and anatomically correct documentation of the working points in 3D during transvascular procedures.

Students:

  • Dagmar Bertsche, M.Sc.
Fusion of anatomic and functional MRI data
Example shows the fusion of functional (time to maximal contraction), scar and anatomic coronary vein data derived from MRI.
Fusion of pre-interventional data and X-ray fluoroscopy
Example shows the superposition of pre-interventional anatomic data of the left ventricle and the coronary veins onto realtime X-ray fluoroscopy.
3D Navigation Tool
Example shows the superposition of pre-interventional MRI data onto X-ray fluoroscopy plus the 3D tracking of the ablation catheter during a pulmonary-vein isolation (PVI) procedure.