Prof. Dr. rer. nat. H.-P. Müller

J. Kassubek, F. Roselli, S. Witzel, J. Dorst, A. C. Ludolph, V. Rasche, I. Vernikouskaya*, H.-P. Müller*. Hypothalamic atrophy in primary lateral sclerosis, assessed by convolutional neural network-based automatic segmentation. Scientific Reports 15: 1551, 2025 (IF: 3.8) (Müller and Vernikouskaya contributed equally)

H. Volkmann, G.U. Höglinger, G. Grön, L.A. Bârlescu, the DESCRIBE-PSP study group, H.-P. Müller*, J. Kassubek*. MRI classification of progressive supranuclear palsy, Parkinson disease and controls using deep learning and machine learning algorithms for the identification of regions and tracts of interest as potential biomarkers. Comput Biol Med 185: 109518, 2025. (IF: 7.7) (Müller and Kassubek contributed equally)

H.-P. Müller, A. Abrahao, C. Beaulieu, M. Benatar, A. Dionne, A. Genge, R. Frayne, S.J. Graham, S. Gibson, L. Korngut, C. Luk, R.C. Welsh, L. Zinman, J. Kassubek, S. Kalra. Temporal and spatial progression of microstructural cerebral degeneration in ALS: a multicentre longitudinal diffusion tensor imaging study. Neuroimage Cl., 43: 103633, 2024 (IF: 4.2)

H.-P.Müller, J. Kassubek. Towards diffusion tensor imaging as a biomarker in neurodegenerative diseases: technical considerations to optimize recordings and data processing. Front. Hum. Neurosci. 18: 1378896, 2024 (IF: 2.9)

N. Wimmer*, H.-P. Müller*, P. Metze, V. Rasche, A.C. Ludolph, J. Kassubek. The central pattern of weakness of ALS: morphological correlates in whole-body muscle MRI. Ann Clin Transl Neurol. 11: 1000-1010, 2024 (IF: 5.3) (Wimmer and Müller contributed equally)

I. Vernikouskaya*, H.‐P. Müller*, F. Roselli, A.C. Ludolph, J. Kassubek, V. Rasche. AI‐assisted quantification of hypothalamic atrophy in amyotrophic lateral sclerosis by convolutional neural network‐based automatic segmentation. Sci Rep. 13: 21505, 2023 (IF: 4.6) (Vernikouskaya and Müller contributed equally)

M. Wiesenfarth, H.-J. Huppertz, J. Dorst, D. Lulé, A. C. Ludolph, H.-P. Müller*, J. Kassubek*. Structural and microstructural neuroimaging signature of C9orf72-associated ALS: a multiparametric MRI study Neuroimage Cl. 39: 103505, 2023 (IF: 4.2) (Müller and Kassubek contributed equally)

R. Kassubek, D. Lulé, A.C. Ludolph, J. Kassubek, H.-P. Müller. Bevacizumab is associated with cerebral microstructural alterations: a DTI study in high-grade glioma. Front Neurol 14: 1191226, 2023. (IF: 4.1)

F. Del Chicca, H. Richter, H.-P. Müller*, J. Kassubek*. MRI-based quantification of adipose tissue distribution in healthy adult cats during body weight gain. Front Vet Sci. 10: 1150085, 2023. (IF: 3.5) (Müller and Kassubek contributed equally)

H.-P. Müller, A. Behler, M. Münch, J. Dorst, A. C. Ludolph, J. Kassubek: Sequential alterations in diffusion metrics as correlates of disease severity in amyotrophic lateral sclerosis. J Neurol. 270: 2308-2313, 2023. (IF: 6.7)

T.D. Kocar, A. Behler, C. Leinert, M. Denkinger, A.C. Ludolph, H.-P. Müller*, J. Kassubek*. Artificial neural networks for non-linear age correction of diffusion metrics in the brain. Front Aging Neurosci. 14:999787, 2022; (IF: 5.2) (Müller and Kassubek contributed equally)

A. Behler, D. Lulé, A. C. Ludolph, J. Kassubek*, H.-P. Müller*. Longitudinal monitoring of amyotrophic lateral sclerosis by diffusion tensor imaging: power calculations for group studies. Front Neurosci. 16:929151, 2022. (IF: 5.2) (Müller and Kassubek contributed equally)

H.-P. Müller*, A.M. Nagel*, F. Keidel, A. Wunderlich, A. Hübers, L.V. Gast, A. C. Ludolph, M. Beer, J. Kassubek, Relaxation-weighted ²³Na magnetic resonance imaging maps regional patterns of abnormal sodium concentrations in amyotrophic lateral sclerosis Ther Adv Chronic Dis. 13:20406223221109480, 2022. (IF 5.1) (Müller and Nagel contributed equally)

M. Münch*, H.-P. Müller*, A. Behler, A.C. Ludolph, J. Kassubek. Segmental alterations of the corpus callosum in motor neuron disease: A DTI and texture analysis in 575 patients. Neuroimage Cl. 35:103061, 2022. (IF 4.9) (Münch and Müller contributed equally)

I. Vernikouskaya*, H.-P. Müller*, D. Felbel, F. Roselli, A.C. Ludolph, J. Kassubek, V. Rasche. Body fat compartment determination by encoder-decoder convolutional neural network: application to amyotrophic lateral sclerosis. Sci Rep. 12:5513, 2022. (IF: 5.0) (Vernikouskaya and Müller contributed equally)

A. Rosenbohm, K. Del Tredici, H. Braak, H.-J. Huppertz, A.C. Ludolph, H.-P. Müller*, J. Kassubek*. Involvement of cortico-efferent tracts in flail arm syndrome: a tract of interest-based DTI study. J Neurol. 269:2619-2626, 2022. (IF: 6.7) (Kassubek and Müller contributed equally)

L. Bârlescu*, H.-P. Müller*, I. Uttner, A.C Ludolph, E.H. Pinkhardt, H.-J. Huppertz, J. Kassubek. Segmental alterations of the corpus callosum in progressive supranuclear palsy: a multiparametric MRI study. Fronti Aging Neurosc. 13:720634, 2021 (IF: 5.8) (Barlescu and Müller contributed equally)

T.D Kocar, A. Behler, A. Ludolph, H.-P. Müller*, J. Kassubek* Multiparametric microstructural MRI and machine learning classification yields high diagnostic accuracy in amyotrophic lateral sclerosis: proof of concept, Front. Neurol. 12:745475, 2021. (IF: 4.0) (Kassubek and Müller contributed equally)

A. Rosenbohm, K. Del Tredici, H. Braak, H.-J. Huppertz, A. C. Ludolph, H.-P. Müller*, J. Kassubek*. Involvement of cortico-efferent tracts in flail arm syndrome: a tract of interest-based DTI study. J Neurol. 2021. (IF: 4.9) (Kassubek and Müller contributed equally)

H.-P. Müller, A. Behler, G.B. Landwehrmeyer, H.-J. Huppertz, J. Kassubek. How to Arrange Follow-Up Time-Intervals for Longitudinal Brain MRI Studies in Neurodegenerative Diseases. Front. Neurosci. 15:682812, 2021. (IF 4.7)

A. Behler, J. Kassubek, H.-P. Müller. Age-Related Alterations in DTI Metrics in the Human Brain - Consequences for Age Correction. Front. Aging Neurosci. 13:682109, 2021. (IF 5.8)

H.-P. Müller, D. Lulé, F. Roselli, A. Behler, A. C. Ludolph, J. Kassubek: Segmental involvement of the corpus callosum in C9orf72-associated ALS: a tract of interest-based DTI study. Ther Adv Chronic Dis 12:20406223211002969, 2021. (IF: 4.3)

D. Lulé*, H.-P. Müller*, J. Finsel, P. Weydt, A. Knehr, I. Winroth, P.M. Andersen, J.H. Weishaupt, I. Uttner, J. Kassubek, A.C. Ludolph. Deficits in verbal fluency in presymptomatic C9orf72 mutation gene carriers – a developmental disorder? J Neurol Neurosurg Psychiatry 91:1195-1200, 2020. (IF 7.4) (Lulé and Müller contributed equally)

H.-P. Müller, F. Roselli, V. Rasche, J. Kassubek. Diffusion tensor imaging-based studies at the group-level applied to animal models of neurodegenerative diseases. Front Neurosci 14:734;2020. (IF 3.7)

H.-P. Müller, K. Del Tredici, D. Lulé, K. Müller, J.H. Weishaupt, A.C. Ludolph, J. Kassubek. In vivo histopathological staging in C9orf72-associated ALS: a tract of interest DTI study. NeuroImage Clin 27:102298, 2020. (IF 4.4)

H.-P. Müller, J. Dreyhaupt, F. Roselli, M. Schlecht, A.C. Ludolph, H.-J. Huppertz, J. Kassubek. Focal alterations of the callosal area III in primary lateral sclerosis: an MRI planimetry and texture analysis. NeuroImage Clin 26:102223, 2020. (IF 3.9)

J. Kassubek, H.-P. Müller. Advanced neuroimaging approaches in amyotrophic lateral sclerosis: refining the clinical diagnosis. Expert Rev Neurother 20:237-249, 2020. (IF 3.5)

H.-P. Müller, M. Gorges, K. Del Tredici, A.C. Ludolph, J. Kassubek. The same cortico-efferent tract involvement in progressive bulbar palsy and in 'classical' ALS: A tract of interest-based MRI study. Neuroimage Clin 24:101979, 2019. (IF 3.9)

H.-P. Müller, D. Brenner, F. Roselli, D. Wiesner, A. Abaei, M. Gorges, K. M. Danzer, A. C. Ludolph, W. Tsao, P. C. Wong, V. Rasche, J. H. Weishaupt, J. Kassubek. Longitudinal Diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the TDP-43G298S ALS mouse model. Transl Neurodegen 8:27, 2019. (IF 5.5)

H.-P. Müller, J. Kassubek. Editorial: Computerized Magnetic Resonance Imaging-Based Neuroimaging of Neurodegenerative Diseases. Front Neurol 10:236, 2019. (IF 3.6)

H.-P. Müller*, H.-J. Huppertz*, J. Dreyhaupt, A. C. Ludolph, S. J. Tabrizi, R. A. C. Roos, Alexandra Durr, G. B. Landwehrmeyer, J. Kassubek. Combined cerebral atrophy score in Huntington´s disease based on atlas-based MRI volumetry: sample size calculations for clinical trials. Parkinsonism Relat Disord 63:179-184, 2019. (IF 4.7) (Müller and Huppertz contributed equally)

H.-P. Müller*, F. Agosta*, M. Gorges, R. Kassubek, E. G. Spinelli, N. Riva, A. C. Ludolph, M. Filippi, J. Kassubek. Cortico-efferent tract involvement in primary lateral sclerosis and amyotrophic lateral sclerosis: a two-center tract of interest-based DTI analysis. NeuroImage Clin 20:1062-1069, 2018 (IF 3.9) (Müller and Agosta contributed equally)

M. Gorges, K. Del Tredici, J. Dreyhaupt, H. Braak, A. C. Ludolph, H.-P. Müller, J. Kassubek. Corticoefferent pathology distribution in amyotrophic lateral sclerosis: in vivo evidence from a meta-analysis of diffusion tensor imaging data. Sci Rep 8:15389, 2018. (IF 4.2) (Kassubek and Müller contributed equally)

H.-P. Müller, J. Kassubek. MRI-based mapping of cerebral propagation in amyotrophic lateral sclerosis. Front Neurosci 12:655, 2018. (IF 3.9)

H.-P. Müller, M. Gorges, R. Kassubek, J. Dorst, A.C. Ludolph, J. Kassubek. Identical patterns of cortico-efferent tract involvement in primary lateral sclerosis and amyotrophic lateral sclerosis: a tract of interest-based MRI study. Neuroimage Clin 18:762-769, 2018. (IF 4.3)

J. Kassubek*, H.-P. Müller*, K. Del Tredici, M. Hornberger, M. L. Schroeter, K. Müller, S. Anderl-Straub, I. Uttner, M. Grossman, H. Braak, J. R. Hodges, O. Piguet, M. Otto, A. C. Ludolph. Longitudinal diffusion tensor imaging resembles patterns of pathology progression in behavioral variant frontotemporal dementia (bvFTD). Front Aging Neurosci 10:47, 2018. (IF 4.5) (Kassubek and Müller contributed equally)

J. Kassubek*, H.-P. Müller*, K. del Tredici, D. Lulé, M. Gorges, H. Braak, A.C. Ludolph. Imaging the pathoanatomy of amyotrophic lateral sclerosis in vivo: targeting a propagation-based biological marker. J Neurol Neurosurg Psychiatry. 89;374-381, 2018. (IF 7.4) (Kassubek and Müller contributed equally)

H.-P. Müller*, F. Agosta*, N. Riva, E.G. Spinelli, G. Comi, A.C. Ludolph, M. Filippi, J. Kassubek. Fast progressive lower motor neuron disease is an ALS variant: a two-centre tract of interest-based MRI data analysis. Neuroimage Clin 17;145-152, 2018. (IF 4.3) (Müller and Agosta contributed equally)

2017:

D. Baldaranov, A. Khomenko, I. Kobor, U. Bogdahn, M. Gorges, J. Kassubek, H.-P. Müller. Longitudinal Diffusion Tensor Imaging-based assessment of tract alterations: an application to amyotrophic lateral sclerosis. Front Hum Neurosci 11:567, 2017. (IF 3.4)

R. Kassubek, M. Gorges, M.-A. Westhoff, A.C. Ludolph, J. Kassubek, H.-P. Müller. Cerebral microstructure alterations after radiation therapy in high-grade glioma: a diffusion tensor imaging-based study. Front Neurol 8:286, 2017. (IF 3.6)

M. Gorges*, H.-P. Müller*, I.M. Mayer, C.S. Grupe, T. Kammer, G. Grön, J. Kassubek, G.B. Landwehrmeyer, R.C. Wolf, M. Orth M. Intact sensory-motor network structure and function in far from onset premanifest Huntington's disease. Sci Rep 7:43841, 2017. (IF 5.5) (Gorges and Müller contributed equally)

2016:

A. Rosenbohm*, H.-P. Müller*, A. Hübers, A.C. Ludolph, J. Kassubek. Corticoefferent pathways in pure lower motor neuron disease: a diffusion tensor imaging study. J Neurol 263:2430-2437, 2016. (IF 3.8) (Rosenbohm and Müller contributed equally)

J. Kassubek, H.-P. Müller. Computer-based magnetic resonance imaging as a tool in clinical diagnosis in neurodegenerative diseases. Expert Rev Neurother 16:295-306, 2016. (IF 2.8)

H.-P. Müller*, M. Gorges*, G. Grön, J. Kassubek, G.B. Landwehrmeyer, R.C. Wolf, M. Orth. Motor network structure and function is associated with motor performance in Huntington’s disease. J Neurol 263:539-549, 2016. (IF 3.8) (Müller and Gorges contributed equally)

H.-P. Müller, M.R. Turner, J. Grosskreutz, S. Abrahams, P. Bede, V. Govind, J. Prudlo, A.C. Ludolph, M. Filippi, J. Kassubek. Neuroimaging Society in ALS (NiSALS) DTI Study Group. A large-scale multicentre cerebral diffusion tensor imaging study in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 87:570-579, 2016. (IF 6.8)

K. Lindemann*, H.-P. Müller*, A.C. Ludolph, M. Hornyak, J. Kassubek. Microstructural abnormalities of the midbrain and cervical spinal cord in restless legs syndrome: a diffusion tensor imaging study. Sleep 39:423-428, 2016. (IF 4.6) (Lindemann and Müller contributed equally)

2014:

J. Rosskopf*, H.-P. Müller*, H.-J. Huppertz, A.C. Ludolph, E.H. Pinkhardt, J. Kassubek. Frontal corpus callosum damage in Progressive Supranuclear Palsy but not in Parkinson´s Disease. Neurodegener Dis 14:184-193, 2014. (IF 3.5) (Rosskopf and Müller contributed equally)

H.-P. Müller*, J. Kassubek*, G. Grön, R. Sprengelmeyer, A.C. Ludolph, S. Klöppel, N.Z. Hobbs, R.A.C. Roos, A. Duerr, S.J. Tabrizi, M. Orth, S.D. Süssmuth, G.B. Landwehrmeyer. Impact of the control for corrupted diffusion tensor imaging data in comparisons at the group level: an application in Huntington disease. BioMed Eng OnLine 13:128, 2014. (IF 1.8) (Müller and Kassubek contributed equally)

M. Gorges*, H.-P. Müller*, A.C. Ludolph, V. Rasche, J. Kassubek. Intrinsic Functional Connectivity Networks in Healthy Elderly Subjects: A Multiparametric Approach with Structural Connectivity Analysis. BioMed Res Int 2014:947252, 2014. (IF 2.9) (Gorges and Müller contributed equally)

J. Kassubek*, H.-P. Müller*, K. Del Tredici, J. Brettschneider, E.H. Pinkhardt, D. Lulé, S. Böhm, H. Braak, A.C. Ludolph. DTI analysis of sequential spreading of disease in amyotrophic lateralsclerosis confirms patterns of TDP-43 pathology. Brain 137:1733-1740, 2014. (IF 9.9) (Kassubek and Müller contributed equally)

2013:

H.-P. Müller, J. Kassubek, I. Vernikouskaya, A.C. Ludolph, D. Stiller, V. Rasche. Diffusion tensor magnetic resonance imaging of the brain in APP transgenic mice: a cohort study. PLoS One 8:e67630, 2013. (IF 4.1)

H.-P. Müller, J. Kassubek. Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases. J Vis Exp 77,e50427, 2013. (IF 1.3)

H.-P. Müller*, H.G. Niessen*, T. Kaulisch, A.C. Ludolph, J. Kassubek, D. Stiller. MRI allows for longitudinal quantitative analysis of body fat composition in rats: An analysis of sibutramine-associated changes at the group level. Magn Reson Imaging 31:1150-1155, 2013. (IF 2.2) (Müller and Niessen contributed equally)

H.-P. Müller*, G. Grön*, R. Sprengelmeyer, J. Kassubek, A.C. Ludolph, N. Hobbs,  J. Cole, R.A.C.Roos, A. Duerr, S.J. Tabrizi, G.B. Landwehrmeyer, S.D. Süssmuth. Evaluating multicenter DTI data in Huntington's disease on site specific effects: An ex post facto approach. Neuroimage Clin 2:161-167, 2013. (IF 0.0) (Müller and Grön contributed equally)

2012:

H.-P. Müller*, I. Vernikouskaya*, A.C. Ludolph, J. Kassubek, V. Rasche. Fast diffusion tensor magnetic resonance imaging of the mouse brain at ultrahigh-field: aiming at cohort studies. PLoS One 7:e53389, 2012. (IF 4.1) (Müller and Vernikouskaya contributed equally)

J. Kassubek, A.C. Ludolph, H.-P. Müller. Neuroimaging of motor neuron diseases. Ther Adv Neurol Disord 5:119-127, 2012. (IF 0.0)

H.-P. Müller*, A. Unrath*, H.-J. Huppertz, A.C. Ludolph, J. Kassubek. Neuroanatomical patterns of cerebral white matter involvement in different motor neuron diseases as studied by diffusion tensor imaging analysis. Amyotroph Lateral Scler 13:254-264, 2012. (Müller and Unrath contributed equally) (IF 3.0)

before 2012:

H.-P. Müller, S.D. Süßmuth, G B. Landwehrmeyer, A.C. Ludolph, S.J. Tabrizi, S. Klöppel, J. Kassubek. Stability effects on results of diffusion tensor imaging analysis by reduction of the number of gradient directions due to motion artifacts: an application to presymptomatic Huntington’s disease. PLoS Curr 2011:3:RRN1292, 2011. (IF 0.0)

H.-P. Müller, V. Glauche, M.J. Novak, T. Nguyen-Thanh, A. Unrath, N. Lahiri, J. Read, M.J. Say, S.J. Tabrizi, J. Kassubek, S. Kloppel. Stability of white matter changes related to Huntington's disease in the presence of imaging noise: a DTI study. PLoS Curr 2011; 3:RRN1232, 2011. (IF 0.0).

H.-P. Müller, F. Raudies, A. Unrath, H. Neumann, A. C. Ludolph, J. Kassubek Quantification of human body fat tissue percentage by magnetic resonance imaging. NMR Biomed 24:17-24, 2011. (IF 4.3)

H.-P. Müller, D. Lulé, A. Unrath, A. C. Ludolph, A. Riecker, J. Kassubek. Complementary image analysis of diffusion tensor imaging and 3-D T1-weighted imaging: white matter analysis in amyotrophic lateral sclerosis. J Neuroimaging 21:24-33, 2011. (IF 1.8)

H.-J. Gdynia*, H.-P. Müller*, A.C. Ludolph, H. Köninger, R. Huber. Quantitative muscle ultrasound neuromuscular disorders using the parameters ‘intensity’, ‘entropy’, and ‘fractal dimension’. Eur J Neurol 16:1151-1158, 2009. (Gdynia and Müller contributed equally) (IF 2.6)

H.-P. Müller, A. Unrath, A. Riecker, E. H. Pinkhardt, A. C. Ludolph, J. Kassubek. Inter-subject variability in the analysis of diffusion tensor imaging at the group level: fractional anisotropy mapping and fiber tracking techniques. Magn Reson Imaging 27:324-334, 2009. (IF 1.6)

H.-P. Müller, A. Unrath, A. D. Sperfeld, A. C. Ludolph, A. Riecker, J. Kassubek. Diffusion tensor imaging and tractwise fractional anisotropy statistics: quantitative analysis in white matter pathology. BioMed Eng OnLine 6:42, 2007. (IF 1.6)

H.-P. Müller, A. Unrath, A. C. Ludolph, J. Kassubek. Preservation of Diffusion Tensor Properties during Spatial Normalization by use of Tensor imaging and Fiber Tracking on a Normal Brain Database. Phys Med Biol 52:N99-109, 2007. (IF 2.9)

H.-P. Müller, G. Nolte, D. DiPietroPaolo, S.N. Erné. Using Independent Component Analysis for Noise Reduction of Magnetocardiographic Data in Case of Exercise with Ergometer. J Med Eng Technol 30:158-165, 2006. (IF 0.5)

H.-P. Müller, I. DeCesaris, M. DeMelis, L. Marzetti, A. Pasquarelli, S.N. Erné, A.C. Ludolph, J. Kassubek. Open Magnetic and Electric Graphic Analysis: Combined MEG-fMRI Imaging in One Single Software Environment. IEEE Eng Med Biol Mag 24:109-116, 2005. (IF 1.3)

H.-P. Müller, E. Kraft, A. Ludolph, S.N. Erné. New Analysis Methods in fMRI Analysis: Hierarchical Cluster Analysis for Improved Signal-to-Noise Ratio Compared to Standard Techniques. IEEE Eng Med Biol Mag 134-142, 2002. (IF 1.3)

H.-P. Müller, P. Gödde, K. Czerski, R. Agrawal, G. Feilcke, K. Reither, K.-J. Wolf, M. Oeff. Localization of a ventricular tachycar5dia-focus with multichannel magnetocardiography and three-dimensional current density reconstruction. J Med Eng Technol 25:108-115, 1999. (IF 0.5)

H.-P. Müller, P. Gödde, K. Czerski, M.Oeff, R. Agrawal, P. Endt, W. Kruse, U. Steinhoff, L. Trahms. Magnetocardiographic Analysis of the two-dimensional distribution of intra-QRS fractionated activation. Phys Med Biol 44:105-120, 1999. (IF 2.9)

H.-P. Müller, R. Kimmich, J. Weis Six-dimensional spin density/velocity NMR microscopy of percolation clusters. Magn Reson Imaging 14: 955-958, 1996. (IF 1.6)

J. Weis, R. Kimmich, H.-P. Müller. NMR imaging of thermal convection patterns. Magn Reson Imaging 14:319-327, 1996. (IF 1.6)

H.-P. Müller, R. Kimmich, J. Weis. NMR flow velocity mapping in random percolation model objects: Evidence for a power-law dependence of the volume-averaged velocity on the probe-volume radius. Phys Rev E 54:5278-5285, 1996. (IF 2.4)

H.-P. Müller, J. Weis, R. Kimmich. Computer simulation and six-dimensional spin density and velocity NMR microimaging of lacunar systems: A comparative analysis of percolation properties. Phys Rev E 52:5195-5204, 1995. (IF 2.4)

H.-P. Müller, W. Aichmann, W. Wonneberger. Descreened phason response in two dimensions. Synth Metals 58:343-352, 1993. (IF 1.3)

I. Vernikouskaya, H.-P. Müller, A.C. Ludolph, J. Kassubek, V. Rasche. AI-assisted automatic MRI-based tongue volume evaluation in motor neuron disease (MND). Int J Comput Assist Radiol Surg. 2024. (IF: 3.0)

S. Witzel, V. Micca, H.-P. Müller, A. Huss, F. Bachhuber, J. Dorst, D.E. Lulé, H. Tumani, J. Kassubek, A.C. Ludolph. Primary lateral sclerosis: application and validation of the 2020 consensus diagnostic criteria in an expert opinion-based PLS cohort. J Neurol Neurosurg Psychiatry. 95: 737-747, 2024. (IF: 11.0)

N. Sollmann, G. Hoffmann, S. Schramm, M. Reichert, M. Hernandez Petzsche, J. Strobel, L. Nigris, C. Kloth, J. Rosskopf, C. Börner, M. Bonfert, M. Berndt, G. Grön, H.-P. Müller, J. Kassubek, K. Kreiser, I. K. Koerte, H. Liebl, A. Beer, C. Zimmer, M. Beer, S. Kaczmarz. Arterial spin labeling (ASL) in neuroradiological diagnostics - methodological overview and use cases. RöFo. 196: 36-51, 2024. (IF: 2.3)

A. Jennings, T. Kuhn, N. P. Bondonno, S. Waniek, C. Bang, A. Franke, J. Kassubek, H.-P. Müller, M. Both, K. S. Weber, W. Lieb, A. Cassidy. The gut microbiome modulates associations between adherence to a Mediterranean-style diet, abdominal adiposity, and C-reactive protein in population-level analysis. Am J Clin Nutrition. 119: 136-144, 2024. (IF: 7.1)

J. Strobel, H.-P. Müller, A. C. Ludolph, A. Beer, N. Sollmann, J. Kassubek. New perspectives in radiological and radiopharmaceutical hybrid imaging in progressive supranuclear palsy: a systematic review. Cells 12: 2776, 2023. (IF: 6.0)

S. Jesse, H.-P. Müller, H.-J. Huppertz, A.C. Ludolph, M. Schön, T.M. Boeckers, J. Kassubek. Neurodegeneration or dysfunction in Phelan-McDermid syndrome? A multimodal approach with CSF and computational MRI. Orphanet J Rare Dis. 18: 274, 2023. (IF: 4.3)

P. Bede, D. Lulé, H.-P. Müller, E.L. Tan, J. Dorst, A.C. Ludolph, J. Kassubek. Presymptomatic grey matter alterations in ALS kindreds: a computational neuroimaging study of asymptomatic C9orf72 and SOD1 mutation carriers. J Neurol. 270: 4235-4247, 2023. (IF: 6.7)

D. Lehrieder, H.-P. Müller, J. Kassubek, N. Hecht, G. Thomalla, D. Michalski, T. Gattringer, K.E. Wartenberg, J. Schultze-Amberger, H. Huttner, J.B. Kuramatsu, S. Wunderlich, H.-H. Steiner, K. Weissenborn, S. Heck, A. Günther, H. Schneider, S. Poli, C. Dohmen, J. Woitzik, E. Jüttler, H. Neugebauer, DESTINY-R Study Group and IGNITE Study Group. Large diameter hemicraniectomy does not improve long-term outcome in malignant infarction. Stroke 270: 4080-4089, 2023. (IF 7.2)

A. Behler, H.-P. Müller, A.C. Ludolph, J. Kassubek. Diffusion Tensor Imaging in Amyotrophic Lateral Sclerosis: Machine Learning for Biomarker Development. Int. J. Mol. Sci. 24: 1911, 2023. (IF: 6.2)

F. Marxreiter, V. Lambrecht, A. Mennecke, J. Hanspach, J. Jukic, M. Regensburger, J. Herrler, A. German, J. Kassubek, G. Grön, H.-P. Müller, F. B. Laun, A. Dörfler, J. Winkler, M. A. Schmidt. Parkinson´s disease or multiple system atrophy: separation by quantitative susceptibility mapping. Therapeutic Advances in Neurological Disorders 16: 17562864221143834, 2023. (IF: 6.5)

F. Marxreiter, V. Lambrecht, A. Mennecke, J. Hanspach, J. Jukic, M. Regensburger, J. Herrler, A. German, J. Kassubek, G. Grön, H.-P. Müller, F. B. Laun, A. Dörfler, J. Winkler, M. A. Schmidt. Parkinson´s disease or multiple system atrophy: separation by quantitative susceptibility mapping. Therapeutic Advances in Neurological Disorders 2022; in press (IF: 6.5)

R. Kassubek, D. Weinstock, A. Behler, H.-P. Müller, L. Dupuis, J. Kassubek, A.C. Ludolph. Morphological alterations of the hypothalamus in idiopathic intracranial hypertension. Therapeutic Advances in Chronic Disease 2022; 13: 20406223221141354. (IF: 5.0)

A. Huss, A. Abdelhak, B. Mayer, H. Tumani, H.-P. Müller, K. Althaus, J. Kassubek, M. Otto, A.C. Ludolph, D. Yilmazer-Hanke, H. Neugebauer. Association of Serum GFAP with Functional and Neurocognitive Outcome in Sporadic Small Vessel Disease. Biomedicines 2022, 10:1869. (IF 4.8)

F.D. Juengling, F. Wuest, S. Kalra, F. Agosta, R. Schirrmacher, A. Thiel, W. Thaiss, H.-P. Müller, J. Kassubek. Simultaneous PET/MRI – the future gold standard for characterizing motor neuron disease? A clinico-radiological and neuroscientific perspective. Front Neurol. 2022; 13:890425 (IF 4.1)

S. Rauch, H.-P. Müller, J. Dreyhaupt, A.C. Ludolph, J. Kassubek, K. Althaus. Andexanet Alfa for Reversal of Factor Xa Inhibitors in Intracranial Hemorrhage: Observational Cohort Study. J Clin Med. 2022, 11:3399. (IF 4.2)

A. Behler, H.-P. Müller, A. C. Ludolph, D. Lulé, J. Kassubek. A multivariate Bayesian classification algorithm for cerebral stage prediction by diffusion tensor imaging in amyotrophic lateral sclerosis. Neuroimage Cl. 2022; 35:103094. (IF: 4.9)

A. Behler, H.-P. Müller, K. Del Tredici, H. Braak, A.C. Ludolph, D. Lulé, J. Kassubek. Multimodal in vivo staging in amyotrophic lateral sclerosis using artificial intelligence. Ann Clin Transl Neurol. 2022; 9: 1069-1079. (IF 5.4)

M. Ponce-de-Leon, A. Hannemann, J. Linseisen, M. Nauck, M.M. Lerch, R. Bülow, H. Völzke, N. Friedrich, J. Kassubek, H.-P. Müller, S.E. Baumeister, C. Meisinger. Links between ectopic and abdominal fat and systemic inflammation: New insights from the SHIP-Trend study. Dig Liver Dis. 2022; 54:1030-1037. (IF 5.2)

D. Lulé, S. Michels, J. Finsel, H. Braak, K. Del Tredici, J. Strobel, A.J. Beer, I. Uttner, H.-P. Müller, J. Kassubek, F.D. Juengling, A.C. Ludolph. Clinicoanatomical substrates of selfish behaviour in amyotrophic lateral sclerosis – an observational cohort study. Cortex. 2022; 146:261-270 (IF: 4.0)

D. Lulé, S. Michels, J. Finsel, H. Braak, K. Del Tredici, J. Strobel, A.J. Beer, I. Uttner, H.-P. Müller, J. Kassubek, F.D. Juengling, A.C. Ludolph. Clinicoanatomical substrates of selfish behaviour in amyotrophic lateral sclerosis – an observational cohort study. Cortex, 2021 (IF: 4.0)

T.D. Kocar, H.-P. Müller, A.C. Ludolph, J. Kassubek. Feature selection from magnetic resonance imaging data in ALS: a systematic review. Ther Adv Chronic Dis2021; 12:20406223211051002.(IF: 5,1)

A. Hübers, J. Kassubek, H.-P. Müller, N. Broc, J. Dreyhaupt, A.C. Ludolph. The ipsilateral silent period: an early diagnostic marker of callosal disconnection in ALS. Ther Adv Chronic Dis 2021; 12:20406223211044072. (IF: 5,1)

A. Behler, A. Knehr, J. Finsel, M.S. Kunz, C. Lang, K. Müller, H.-P. Müller, E.H. Pinkhardt, A.C. Ludolph, D. Lulé, J. Kassubek. Eye movement alterations in presymptomatic C9orf72 expansion gene carriers. J Neurol. 2021; 268:3390-3399. (IF 4.9)

D. Lehrieder, K. Layer, H.-P. Müller, V. Rücker, J. Kassubek, E. Juettler, H. Neugebauer. Association of Infarct Volume Before Hemicraniectomy and Outcome After Malignant Infarction. Neurology, 2021, 10.1212 (IF 9.9)

A. Hübers, B. Böckler, A. Abaei, V. Rasche, D. Lulé, E. Ercan, N. Doorenweerd, H.-P. Müller, J. Dreyhaupt, T. Kammer, A. C. Ludolph, I. Ronen, J. Kassubek. Functional and structural impairment of transcallosal motor fibres in ALS: a study using transcranial magnetic stimulation, diffusion tensor imaging, and diffusion weighted spectroscopy. Brain Imaging Behav, 2021; 15:748-757. (IF 4.0)

D. Bayer, S. Antonucci, H.-P. Müller, R. Saad, L. Dupuis, V. Rasche, T.M. Böckers, A.C. Ludolph, J. Kassubek, F. Roselli. Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and in human patients. Transl. Neurodegen, 2021, 10:17(1-17) (IF 5.6).

R. Kassubek, H.-P. Müller, A. Thiele, J. Kassubek, H. G. Niessen. Advanced magnetic resonance imaging to support clinical drug development for malignant glioma. Drug Discovery Today. 2021, 26: 429-441. (IF 7.9).

R. Kassubek, H.-P. Müller, A. Thiele, J. Kassubek, H. G. Niessen. Advanced magnetic resonance imaging to support clinical drug development for malignant glioma. Drug Discovery Today. 2020. in press. (IF 7.3)

T.D. Kocar, H.-P. Müller, J. Kassubek. Differential functional connectivity in thalamic and dopaminergic pathways in restless legs syndrome: a meta-analysis. Ther Adv Neurol Disord 2020.13: 1756286420941670 (1-10). (IF 5.0)

I. Ratjen, J. Morze, J. Enderle, M. Both, J. Borggrefe, H.-P. Müller, J. Kassubek, M. Koch, W. Lieb:. Adherence to a plant-based diet in relation to adipose tissue volumes and liver fat content. Am J Clinl Nutr, 2020. 112 354-363. (IF 6.6)

A. Abdelhak, A. Huss, A. Brück, U. Sebert, B. Mayer, H. -P. Müller, H. Tumani, M. Otto, D. Yilmazer-Hanke, A.C. Ludolph, J. Kassubek, E. Pinkhardt, H. Neugebauer. Optical coherence tomography-based assessment of retinal vascular pathology in cerebral small vessel disease. Neurol Res Pract 2:13, 2020. (IF 0.0)

J. Fischer, H. Völzke, J. Kassubek, H.-P. Müller, J.-P. Kühn, M. Nauck, N. Friedrich, S. Zylla. Associations of a panel of adipokines with fat deposits and metabolic phenotypes in a general population. Obesity 2020.28:1550-1559, 2020. (IF 4.0)

A. Hübers, B. Böckler, A. Abaei, V. Rasche, D. Lulé, E. Ercan, N. Doorenweerd, H.-P. Müller, J. Dreyhaupt, T. Kammer, A. C. Ludolph, I. Ronen, J. Kassubek. Functional and structural impairment of transcallosal motor fibres in ALS: a study using transcranial magnetic stimulation, diffusion tensor imaging, and diffusion weighted spectroscopy. Brain Imaging Behav, 2020; in press. (IF 3.4)

S. Kalra, H.-P. Müller, A. Ishaque, L. Zinman, L. Korngut, A. Genge, C. Beaulieu, R. Frayne, S.J. Graham, J. Kassubek. A prospective harmonized multicentre DTI study of cerebral white matter degeneration in ALS. Neurology 2020; in press. (IF 8.7).

D. Yilmazer-Hanke, T. Mayer; H.-P. Müller, H. Neugebauer, A. Abaei, A. Scheuerle, J. Weis, K.M.E. Forsberg, K. Althaus, J. Meier, A.C. Ludolph, K. Del Tredici, H. Braak, J. Kassubek, V. Rasche. Histological Correlates of Postmortem Ultra-High-Resolution Single-Section MRI in Cortical Cerebral Microinfarcts. Acta Neuropathol Comms 8:33, 2020. (IF 5.8)

A. Jennings, M. Koch, M. K. Jensen, C. Bang, J. Kassubek, H.-P. Müller, U. Nöthlings, A. Franke, W. Lieb, A. Cassidy. The role of the gut microbiome in the association between habitual anthocyanin intake and visceral abdominal fat in population-level analysis. Am J Clinl Nutr 111:340-350, 2020. (IF 6.6)

S. Jesse , H.-P. Müller, M. Schoen, H. Asoglu, J. Bockmann, H.-J. Huppertz, V. Rasche , A.C. Ludolph, T.M. Boeckers, J. Kassubek. Severe white matter damage in SHANK3 deficiency: a human and translational study. Ann Clin Transl Neurol 7:46-58, 2020. (IF 4.6)

J. Shu, H. Neugebauer, F. Li, D. Lulé, H.-P. Müller, J. Zhang, A. C. Ludolph, Y. Huang, J. Kassubek, W. Zhang. Clinical and neuroimaging disparity between Chinese and German patients with cerebral small vessel disease: a comparative study. Sci Rep 9:20015, 2019. (IF 4.0)

M. Gorges, M. S. Kunz, H.-P. Müller, I. Liepelt-Scarfone, A. Storch, R. Dodel, R. Hilker-Roggendorf, LANDSCAPE Consortium, D. Berg, E. Kalbe, H. Braak, K. Del Tredici, S. Baudrexel, H.-J. Huppertz, J. Kassubek. Longitudinal brain atrophy distribution in advanced Parkinson?s disease: what makes the difference in cognitive status converters? Hum Brain Mapp 41:1416-1434, 2019. (IF 4.6)

M. Gorges, B. Kuntz, K. Del Tredici, D. G. Schmidt, H.-P. Müller, A. C. Ludolph, L. Dupuis, J. Kassubek. Morphological MRI investigations of the hypothalamus in 232 individuals with Parkinson’s disease. Mov Disord 34:1566-1570, 2019. (IF 8.1)

M. Gorges, H.-P. Müller, I. Liepelt-Scarfone, A. Storch, R. Dodel, LANDSCAPE Consortium, R. Hilker-Roggendorf, D. Berg, M. S. Kunz, E. Kalbe, S. Baudrexel, J. Kassubek. Structural brain signature of cognitive decline in Parkinson’s disease: DTI-based evidence from the LANDSCAPE study. Ther Adv Neurol Disord 12:1756286419843447, 2019. (IF 4.8)

R. di Giuseppe, S. Plachta-Danielzik, M. Koch, U. Nöthlings, S. Schlesinger, J. Borggrefe, M. Both, H.-P. Müller, J. Kassubek, G. Jacobs, W. Lieb. Dietary pattern associated with selenoprotein P and MRI-derived body fat volumes, liver signal intensity, and metabolic disorders. Eur J Nutr 58:1067-1079, 2019. (IF 4.3)

M.P. van den Heuvel, ..., H.-P. Müller, ... 10Kin1day: A Bottom-Up Neuroimaging Initiative. Front Neurol 10:425, 2019.  (IF 3.5)

M. Schoen, H. Asoglu, H.F. Bauer, H.-P. Müller, A. Abaei, A.K. Sauer, R. Zhang, T.J. Song, J. Bockmann, J. Kassubek, V. Rasche, A.M. Grabrucker, T.M. Boeckers. Shank3 Transgenic and Prenatal Zinc-Deficient Autism Mouse Models Show Convergent and Individual Alterations of Brain Structures in MRI. Front Neural Circuits 13:6, 2019. (IF 3.1)

F. Verde, P. Steinacker, J.H. Weishaupt, J. Kassubek, P. Oeckl, S. Halbgebauer, H. Tumani, C.A.F. von Arnim, J. Dorst, E. Feneberg, B. Mayer, H.-P. Müller, M. Gorges, A. Rosenbohm, A.E. Volk, V. Silani, A.C. Ludolph, M. Otto. Neurofilament light chain in serum for the diagnosis of amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 90:157-164, 2019. (IF 7.4)

R. di Giuseppe, S. Plachta-Danielzik, M. Koch, U. Nöthlings, S. Schlesinger, J. Borggrefe, M. Both, H.-P. Müller, J. Kassubek, G. Jacobs, W. Lieb. Dietary pattern associated with selenoprotein P and MRI-derived body fat volumes, liver signal intensity, and metabolic disorders. Eur J Nutr 58:1067-1079, 2019. (IF 4.3)

M. Gorges, H.-P. Müller, J. Kassubek. Structural and functional brain mapping correlates of impaired eye movement control in parkinsonian syndromes: a systems-based concept. Front Neurol 9:319, 2018. (IF 3.6)

D. Lulé, S. Böhm, H.-P. Müller, H. Aho-Özhan, J. Keller, M. Gorges, M. Loose, J. Weishaupt, I. Uttner, E.H. Pinkhardt, J. Kassubek, K. Del Tredici, H. Braak, S. Abrahams, A.C Ludolph. Cognitive phenotypes of sequential staging in amyotrophic lateral sclerosis. Cortex 101:163-171, 2018. (IF 4.3 )

A. Rosenbohm, S. Hirsch, A. E. Volk, T. Grehl, J. Grosskreutz, F. Hanisch, A. Herrmann, K. Kollewe, W. Kress, T. Meyer, S. Petri, J. Prudlo, C. Wessig, H.-P. Müller, J. Dreyhaupt, J. Weishaupt, C. Kubisch, J. Kassubek, P. Weydt, A. Ludolph. The metabolic and endocrine characteristics in spinal and bulbar muscular atrophy. J Neurol 265:1026-1036, 2018. (IF 3.4)

J. Rosskopf, M. Gorges, H.-P. Müller, E.H. Pinkhardt, A.C. Ludolph, J. Kassubek. Hyperconnective and hypoconnective cortical and subcortical functional networks in multiple system atrophy. Parkinsonism Related Disord 49:75-80, 2018. (IF 4.5)

2017:

S. Waniek, R. di Giuseppe, S. Plachta-Danielzik, I. Ratjen, G. Jacobs, M. Koch, J. Borggrefe, M. Both, H.-P. Müller, J. Kassubek, U. Nöthlings, T. Esatbeyoglu, S. Schlesinger, G. Rimbach, W. Lieb. Association of vitamin E levels with metabolic syndrome, MRI-derived body fat volumes and liver fat content. Nutrients 9:1143, 2017. (IF 3.6)

M. Gorges, M.N. Maier, J. Rosskopf, O. Vintonyak, E.H. Pinkhardt, A.C. Ludolph, H.-P. Müller, J. Kassubek. Regional microstructural damage and patterns of eye movement impairment: a DTI and video-oculography study in neurodegenerative parkinsonian syndromes. J Neurol 264:1919–1928, 2017. (IF 3.4)

J. Rosskopf, M. Gorges, H.-P. Müller, D. Lulé, I. Uttner, A.C. Ludolph, E.H. Pinkhardt, F.D. Juengling, J. Kassubek. Intrinsic functional connectivity alterations in Progressive Supranuclear Palsy: differential effects in frontal cortex, motor and midbrain networks. Mov Disord 32:1006-1015, 2017.  (IF 7.1)

M. Gorges, P. Vercruysse, H.-P. Müller, H.-J. Huppertz, A. Rosenbohm, G. Nagel, P. Weydt, Å. Petersén, A.C. Ludolph, J. Kassubek, L. Dupuis. Hypothalamic atrophy is related to body mass index and age at onset in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 88:1033-1041, 2017. (IF 6.4)

M. Gorges, F. Roselli, H.-P. Müller, A. C. Ludolph, V. Rasche, J. Kassubek. Functional connectivity mapping in the animal model: principles and applications of resting-state fMRI. Front Neurol 8:200, 2017. (IF 3.6)

R. di Giuseppe, S. Plachta-Danielzik, M. Koch, U. Nöthlings, S. Schlesinger, J. Borggrefe, M. Both, H.-P. Müller, J. Kassubek, G. Jacobs, W. Lieb. Circulating selenoprotein P levels in relation to MRI-derived body fat volumes, liver fat content, and metabolic disorders. Obesity 5:1128-1135, 2017. (IF 3.6)

J. Rosskopf, M. Gorges, H.-P. Müller, D. Lulé, I. Uttner, A.C. Ludolph, E.H. Pinkhardt,  F.D. Juengling, J. Kassubek J. Intrinsic functional connectivity alterations in progressive supranuclear palsy: Differential effects in frontal cortex, motor, and midbrain networks. Mov Disord 32:1006-1015, 2017. (IF 6.0)

P. Fissler, H.-P. Müller, O.C. Küster, D. Laptinskaya, F. Thurm, A. Woll, T. Elbert, J. Kassubek, C:A:F. von Arnim, I. Kolassa. No evidence that short-term cognitive or physical training programs or lifestyles are related to changes in white matter integrity in older adults at risk of dementia. Frontiers Hum Neurosci 11:110, 2017. (IF. 3.6)

O. Vintonyak, M. Gorges, H.-P. Müller, E.H. Pinkhardt, A.C. Ludolph, H.-J. Huppertz, J. Kassubek. Patterns of Eye Movement Impairment Correlate with Regional Brain Atrophy in Neurodegenerative Parkinsonism. Neurodegener Dis 17:117-126, 2017. (IF 2.9)

2016:

I. Schulthess, M. Gorges, H.-P. Müller, D. Lulé, K. Del Tredici, A.C. Ludolph, J. Kassubek. Functional connectivity changes resemble patterns of pTDP-43 pathology in amyotrophic lateral sclerosis. Sci Rep 6:38391, 2016. (IF 5.2)

R. Sprengelmeyer, A.W. Young, E.-M. Baldas, I. Ratheiser, C.A.M. Sutherland, H.-P. Müller, G. Grön, S.D. Süssmuth, G.B. Landwehrmeyer, M. Orth. The neuropsychology of first impressions: Evidence from Huntington’s disease. Cortex 85:100-115, 2016. (IF 4.3)

D. Bernhardt, H.-P. Müller, A.C. Ludolph, L. Dupuis, J. Kassubek. Body fat distribution in Parkinson's Disease: an MRI-based body fat quantification study. Parkinsonism Relat Disord 33:84-89, 2016. (IF 4,0)

M. Gorges, J. Rosskopf, H.-P. Müller, K. Lindemann, M. Hornyak, J. Kassubek. Patterns of increased intrinsic functional connectivity in patients with Restless Legs Syndrome are associated with attentional control of sensory inputs. Neurosci Lett 617:264-269, 2016. (IF 2.0)

A. Hübers, H.-P. Müller, J. Dreyhaupt, K. Böhm, F. Lauda, H. Tumani, J. Kassubek, A.C. Ludolph, E.H. Pinkhardt. Retinal involvement in amyotrophic lateral sclerosis: a study with optical coherence tomography and diffusion tensor imaging. J Neural Transm 123:281-287, 2016. (IF 2.4)

P.. Steinacker, E. Feneberg, J. Weishaupt, J. Brettschneider, H. Tumani, P.M. Andersen, C.A. von Arnim, S. Böhm, J. Kassubek, C. Kubisch, D. Lulé, H.-P. Müller, R. Muche, E.H. Pinkhardt, P. Oeckl, A. Rosenbohm, S. Anderl-Straub, A.E. Volk, P. Weydt, A.C. Ludolph, M. Otto. Neurofilaments in the diagnosis of motoneuron diseases: a prospective study on 455 patients. J Neurol Neurosurg Psychiatry 87:12-20, 2016. (IF 6.8)

2015:

K. Fischer, D. Rüttgers, H.-P. Müller, G. Jacobs, J. Kassubek, W. Lieb, U. Nöthlings. Association of Habitual Patterns and Types of Physical Activity and Inactivity with MRI-Determined Total Volumes of Visceral and Subcutaneous Abdominal Adipose Tissue in a General White Population. PLoS One 10:e0143925, 2015. (IF 3.2)

M. Gorges, H.-P. Müller, D. Lulé, K. Del Tredici, J. Brettschneider, J. Keller, K. Pfandl, A.C. Ludolph, J. Kassubek, E.H. Pinkhardt. Eye Movement Deficits Are Consistent with a Staging Model of pTDP-43 Pathology in Amyotrophic Lateral Sclerosis. PLoS One 10:e0142546, 2015. (IF 3.2)

D. Rüttgers, K. Fischer, M. Koch, W. Lieb, H.-P. Müller, G. Jacobs, J. Kassubek, U. Nöthlings. Association of food consumption with total volumes of visceral and subcutaneous abdominal adipose tissue in a Northern German population. Br J Nutr 114:1929-1940, 2015. (IF 3.5)

N.Z. Hobbs, R.E. Farmer, E.M. Rees, J.H. Cole, S. Haider, I.B. Malone, R. Sprengelmeyer, H. Johnson, H.-P. Müller, S.D. Sussmuth, R.A. Roos, A. Duerr, C. Frost, R.I. Scahill, G.B. Landwehrmeyer, S.J. Tabrizi. Short-interval observational data to inform clinical trial design in Huntington's disease. J Neurol Neurosurg Psychiatry 86:1291-1298, 2015. (IF 6.8)

E. Diehl-Wiesenecker, C.F. von Arnim, L. Dupuis, H.-P. Müller, A.C. Ludolph, J. Kassubek. Adipose tissue distribution in patients with Alzheimer's disease. J Alzheimers Dis 48:825-832, 2015. (IF 4.1)

M. Gorges, H.-P. Müller, D. Lulé; LANDSCAPE Consortium, E.H. Pinkhardt, A.C. Ludolph, J. Kassubek. The association between alterations of eye movement control and cerebral intrinsic functional connectivity in Parkinson's disease. Brain Imaging Behav 10,79-91, 2015. (IF 3.6)

J. Rosskopf, H.-P. Müller, J. Dreyhaupt, M. Gorges, A.C. Ludolph, J. Kassubek. Ex post facto assessment of diffusion tensor imaging metrics from different MRI protocols: preparing for multicenter studies in ALS. Amyotroph Lateral Scler Frontotemporal Degener 16:92-101, 2015. (IF 2.4)

K. Fischer, D. Moewes, M. Koch, H.-P. Müller, G. Jacobs, J. Kassubek, W. Lieb, U. Nöthlings. MRI-determined total volumes of visceral and subcutaneous abdominal and trunk adipose tissue are differentially and sex-dependently associated with patterns of estimated usual nutrient intake in a Northern German population. Am J Clin Nutr 101:794-807, 2015. (IF 6.9)

M. Gorges, H.-P. Müller, D. Lulé, LANDSCAPE Consortium, E.H. Pinkhardt, A.C. Ludolph, J. Kassubek. To rise and to fall: Functional connectivity in cognitively normal and cognitively impaired patients with Parkinson's disease. Neurobiol Aging 36:1727-1735, 2015. (IF 4.9)

D. Wiesner, J. Sinniger, A. Henriques, S. Dieterlé, H.-P. Müller, V. Rasche, B. Ferger, S. Dirrig-Grosch, R. Soylu-Kucharz, A. Petersén, P. Walther, B. Linkus, J. Kassubek, P.C. Wong, A.C. Ludolph, L. Dupuis. Low dietary protein content alleviates motor symptoms in mice with mutant dynactin/dynein mediated neurodegeneration. Hum Mol Genet 24:2228-2240, 2015. (IF 6.7)

2014:

J. Heimrath, M. Gorges, J. Kassubek, H.-P. Müller, N. Birbaumer, A.C. Ludolph, D. Lulé. Additional resources and the default mode network: evidence of increased connectivity and decreased white matter integrity in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener 15:537-545, 2014. (IF 2.4)

K.S. Lindenberg, P. Weydt, H.-P. Müller, A. Bornstedt, A.C. Ludolph, G.B. Landwehrmeyer, W. Rottbauer, J. Kassubek, V. Rasche. Two-Point Magnitude MRI for Rapid Mapping of Brown Adipose Tissue and its application to the R6/2 mouse model of Huntington disease. PLoS One 9:e105556, 2014. (IF 3.5)

E.H. Pinkhardt, H. Issa, M. Gorges, R. Jürgens, D. Lulé, J. Heimrath, H.-P. Müller, A.C. Ludolph, W. Becker, J. Kassubek. Do eye movement impairments in patients with small vessel cerebrovascular disease depend on lesion load or on cognitive deficits? A video-oculographic and MRI study. J Neurol 261:791-803, 2014. (IF 3.6)

R. Sprengelmeyer, M. Orth, H.-P. Müller, R.C. Wolf, G. Grön, M.S. Depping, J. Kassubek, D.D. Justo, E. Rees, S. Haider, J. Cole, N.Z. Hobbs, R.A.C. Roos, A. Dürr, S.J. Tabrizi, S.D. Süssmuth, G.B. Landwehrmeyer. The neuroanatomy of sub-threshold depressive symptoms in Huntington's disease: a combined DTI and VBM study. Psychol Med 44:1867-1878, 2014. (IF 5.6)

A. Rosenbohm, S.D. Süssmuth, J. Kassubek, H.-P. Müller, C. Pontes, A. Abicht, S. Bulst, A.C. Ludolph, E.H. Pinkhardt. Novel ETFDH mutation and imaging findings in an adult with glutaric aciduria type II. Muscle Nerve 49:446-450, 2014.  (IF 2.3)

M. Schneider, H.-P. Müller, F. Lauda, H. Tumani, A.C. Ludolph, J. Kassubek, E.H. Pinkhardt. Retinal single-layer analysis in Parkinsonian syndromes: an optical coherence tomography study. J Neural Transm 121:41-47, 2014. (IF 3.1)

2013:

E. Lindauer, L. Dupuis, H.-P. Müller, H. Neumann, A.C. Ludolph, J. Kassubek. Adipose tissue distribution predicts survival in amyotrophic lateral sclerosis. PLoS One 8:e67783, 2013. (IF 4.1)

M. Gorges, H.-P. Müller, D. Lulé, A.C. Ludolph, E.H. Pinkhardt, J. Kassubek. Functional connectivity within the default mode network is associated with saccadic accuracy in Parkinson's disease: a resting state fMRI and videooculographic study. Brain Connect  3:265-272, 2013. (IF 0.0)

S. Jesse, J. Kassubek, H.-P. Müller, A.C. Ludolph, A. Unrath. Signal alterations of the basal ganglia in the differential diagnosis of Parkinson's disease: a retrospective case-controlled MRI data bank analysis. BMC Neurol 12:163, 2013. (IF 2.2)

H.-S. Karcher, R. Holzwarth, H.-P. Müller, A.C. Ludolph, R. Huber, J. Kassubek,  E.H. Pinkhardt. Body Fat Distribution as a Risk Factor for Cerebrovascular Disease: An MRI-Based Body Fat Quantification Study. Cerebrovasc Dis 35:341–348, 2013. (IF 2.7)

2012:

T. Klein, H.G. Niessen, C. Ittrich, E. Mayoux, H.-P. Müller, S. Cheetham, D. Stiller, J. Kassubek, M. Mark. Evaluation of body fat composition after linagliptin treatment in a rat model of diet-induced obesity: a magnetic resonance spectroscopy study in comparison with sibutramine. Diabetes Obes Metab 14:1050-1053, 2012. (IF 3.4)

C. Knauer, K. Knauer, S. Müller, A.C. Ludolph, D. Bengel, H.-P. Müller, R. Huber. A biochemical marker panel in MRI-proven hyperacute ischemic stroke-a prospective study. BMC Neurol 12:14, 2012. (IF: 2.2)

J. Kassubek, A.-D. Sperfeld ,A. Unrath, E.H. Pinkhardt, H.-P. Müller, K. Scharfetter-Kochanek, A.C. Ludolph, M. Berneburg. The cerebro-morphological fingerprint of a progeroid syndrome: White matter changes correlate with neurological symptoms in xeroderma pigmentosum. PLoS One, 7:e30926,. 2012. (IF 4.4)

A. Unrath, H.-P. Müller, A.C. Ludolph J. Kassubek. Reversible Cortical Diffusion Restriction, Hyperperfusion and T2-Hyperintensity Caused by Two Different Types of Epileptic Seizure. Clin Neuroradiol 2012; 22:239-243 (IF 0.6)

before 2012:

K. E. Braunstein, J. Eschbach, K. Ròna-Vörös, R. Soylu, E. Mikroul, Y. Larmet, F. Rene, J.-L. Gonzalez de Aguilar, J.-P. Loeffler, H.-P. Müller, S. Bucher, T. Kaulisch, H. G. Niessen, J. Tillmanns, K. Fischer, B. Schwalenstöcker, J. Kassubek, B. Pichler, D. Stiller, Å. Petersen, A. C. Ludolph, L. Dupuis. A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons Hum Mol Genet 19:4385-4398, 2010. (IF 7.4)

A. Unrath, H.-P. Müller, J. Kassubek. Voxelbasierte MR-Morphometrie und Diffusionstensorbildgebung: Grundlagen und Anwendungen in der klinischen Neurologie. J Neurol, Neurochi Psychiatrie 1-10; 2010. (IF 0.0)

D. Lulé, V. Diekmann, H.-P. Müller, J. Kassubek, A. C. Ludolph, N. Birbaumer. Evidence for extra-motor involvement in amyotrophic lateral sclerosis (ALS), J Neurol Neurosurg Psychiatry 81:889-906. 2010. (IF 4.9)

A. Unrath, H.-P. Müller, A. Riecker, A. C. Ludolph, A.-D. Sperfeld, J. Kassubek. Whole brain-based analysis of regional white matter tract alterations in rare motor neuron diseases by diffusion tensor imaging. Hum Brain Mapp 31:1727-1740. 2010. (IF 6.2)

D. DiPietroPaolo, H.-P. Müller, M. Goernig, J. Haueisen, S.N. Erne. Cardiac signal extraction in patients with Implantable Cardioverter Defibrillators. Med Eng Phys 31:1087-1094; 2009. (IF 1.8)

M. De Melis, B.S. Kim, Y. Uchikawa, H.-P. Müller, S.N. Erné. Discussion of Current Distribution of Exercise 3D MCG Using an Inhomogeneous Human Volume Conductor. J Magnetics Soc Japan 32:195-200, 2008. (IF 0.0)

B. Steinbrink, K. Vogt, A. Kastrup, H.-P. Müller, F. D. Juengling, J. Kassubek, A. Riecker, The contribution of white and gray matter differences to developmental dyslexia: Insights from DTI and VBM at 3.0 Tesla. Neuropsychologia. 46:3170-3178. 2008. (IF 3.6)

A. Unrath, H.-P. Müller, A. C. Ludolph, A. Riecker, J. Kassubek: Cerebral white matter alterations in idiopathic restless legs syndrome, as measured by diffusion tensor imaging. Mov Disord 23:1250-1255, 2008. (IF 3.3)

D. DiPietroPaolo, H.-P. Müller, G. Nolte, S.N. Erné. Noise reduction in magnetocardiography by singular value decomposition and independent component analysis, Med Biol Eng Comput 44:489-499, 2006. (IF 1.2)

W. Tedeschi, H.-P. Müller, D.B. de Araujo, A.C. Santos, U.P.C. Neves, S.N. Erné, O. Baffa. Generalized Mutual Information tests applied to fMRI analysis. Physica A 352:629-644, 2005. (IF 1.3)

D. DiPietroPaolo, H.-P. Müller, S.N. Erné. A Novel Approach for the Averaging of Magnetocardiographic Recorded Heart Beats. Phys Med Biol 50:2415-2426, 2005. (IF 2.9)

W. Tedeschi, H.-P. Müller, D.B. de Araujo, A.C. Santos, U.P.C. Neves, S.N. Erné, O. Baffa. Generalized Mutual Information fMRI Analysis: A Study of the Tsallis q Parameter. Physica A 344:705-711, 2004. (IF 1.3)

W. Tedeschi, H.-P. Müller, B. Schless, O. Grebe, V. Hombach, U.P.C. Neves, O. Baffa, S.N. Erné. A New Strategy for Easy Volume Conductor Modelling in Magnetocardiography. J Med Eng Technol 29:33-37, 2004. (IF 0.5)

R. Sturm, H.-P. Müller, A. Pasquarelli, M. Demelis, D. Lang, S.N. Erné. Multi-channel Magnetocardiography for Detecting Beat Morphology Variations in Fetal Arrhythmia. Prenat Diagn 24:1-9, 2004. (IF 1.5)

B.G. Schless, H.-P. Müller, M. DeMelis, A. Pasquarelli, S.N. Erné, V. Hombach. Analysis of the ST-Segment in Terms of Principal Components: Application on Multichannel Magnetocardiographic Recordings. J Med Eng Technol 28:56-60, 2003. (IF 0.5)

B.G. Schless, H.-P. Müller, A. Pasquarelli, S.N. Erné, V. Hombach. On the Variability of QRS Time-Duration in Magnetocardiographic Recordings. J Med Eng Technol 27:113-117, 2003. (IF 0.5)

P. Goedde, R. Agrawal, H.-P. Müller, K. Czerski, P. Endt, U. Steinhoff, M. Oeff, H.P. Schultheiss, S. Behrens. Magnetocardiographic mapping of QRS fragmentation in patients with a history of malignant tachyarrhythmias. Clin Cardiol 24::682-688, 2001. (IF 0.7)

A. Klemm, H.-P. Müller, R. Kimmich Evaluation of fractal parameters of percolation model objects and natural porous media by means of NMR microscopy. Physica A 266: 242-246,1999. (IF 1.3)

A. Klemm, H.-P. Müller, R. Kimmich. NMR microscopy of pore-space backbones in rock, sponge, and sand in comparison with random percolation model objects. Phys. Rev. E 55:4413-4422, 1997. (IF 2.4)

W. Aichmann, H.-P. Müller, W. Wonneberger. A Theory of the Strongly Pinned Fröhlich Mode in 2 and 3 Dimensions. Synth Metals 55-57:4237-4242, 1993. (IF 1.3)

H.-P. Müller, J. Kassubek. Multimodal imaging in neurology – special focus on MRI applications and MEG. Synthesis Lectures in Biomedical Engineering #16, Ed. Enderle JD, Morgan & Claypool Publishers 2008; (ISBN paperback: 1-59829-550-0, ebook: 1-59829-551-9)

H.-P. Müller, A. Unrath, A. Riecker, and J. Kassubek. Diffusion tensor imaging: Analysis methods for group comparison in neurology. (chapter 13) in Ed. L. L‘Abate and D.A. Kasier „Handbook of Technology in Psychology, Psychiatry and Neurology“, Nova Science Publishers, 2012.

J. Kassubek, H.-P. Müller, and F.D. Juengling. Multimodality in Functional Neuroimaging. (chapter 10) in Ed. C. Stippich-"Clinical functional MRI and Diffusion Tensor Imaging - Presurgical Functional Neuroimaging“, Springer, 2nd edition, 2015.

2019:

Sana Wissenschaftspreis:„MR-Tomographische in vivo Charakterisierung der Krankheitsstadien bei der Amyotrophen Lateralsklerose und ihrer Varianten Progressive Muskelatrophie und Primäre Lateralsklerose“

2022/2023:

Prof. Müller is listed under the world-wide top 15 experts in diffusion tensor imaging (expertscape.com).