Resi­dent, Board Neu­ro­logy and Psych­ia­try (Depart­ment of  Neu­ro­logy and Psych­ia­try, Uni­ver­sity of Müns­ter FRG)(Prof. G. Brune, Prof. R. Tölle)

Sti­pend, Deut­sche For­schungs­ge­mein­schaft: Insti­tute of Neu­ro­to­xi­co­logy, Albert Ein­stein Col­lege of Medi­cine, Bronx, New York (Prof. P.S. Spen­cer, Prof. H.H. Schaum­burg)

Staff, Depart­ment of Neu­ro­logy, Uni­ver­sity of Müns­ter (Prof. G. Brune)

Habi­li­ta­tion, Faculty of Medi­cine, Uni­ver­sity of Müns­ter, C2 Pro­fes­sor of Neu­ro­logy

Staff Sci­en­tist, Visi­ting Assoc. Prof., Cen­ter for Rese­arch on Occu­pu­ta­tio­nal and Envi­ron­men­tal Toxi­co­logy, Port­land (Ore­gon)

Staff, Depart­ment of Epi­lep­to­logy, Uni­ver­sity of Bonn (Prof. C.E. Elger)

C3 Pro­fes­sor of Neu­ro­logy, Vice Chair­man, Depart­ment of Neu­ro­logy, Hum­boldt Uni­ver­sity Ber­lin (Prof. K.-M. Ein­häupl)

C4 Pro­fes­sor of Neu­ro­logy, Chair, Depart­ment of Neu­ro­logy, Uni­ver­sity of Ulm

Chair (elec­ted) Aca­de­mic Neu­ro­sci­ence Cen­ter, Uni­ver­sity of Ulm

Deputy Chair and Chair (elec­ted), European ALS-​MND-Group

Chair (elec­ted) ALS panel of the EFNS and EAN (since 2014, toge­ther with Prof. Vin­cenzo Silani)

Sci­en­ti­fic Advi­sory Board Thierry Lat­ran Founda­tion

Chair, Sci­en­ti­fic Coun­cil of Deut­sche Stif­tung Quer­schnitt­läh­mung (DSQ)

Chair Sci­en­ti­fic Coun­cil Deut­sche Gesell­schaft für Mus­kel­kranke

Sci­en­ti­fic Advi­sory Board Mem­ber of the Stif­ter­ver­band der Schilling-​Research-Groups for Trans­la­tio­nal Neu­ro­sci­ence

Chair (elec­ted), World Fede­ra­tion of Neu­ro­logy, ALS Rese­arch Group

Reviewer for Neu­ro­sci­ence Board of the Ger­man Rese­arch Founda­tion (DFG)

Vice Dean of the Medi­cal Faculty of Ulm

>Chair (elec­ted), World Fede­ra­tion of Neu­ro­logy, ALS Rese­arch Group

Dele­gate of the Ger­man Society of Neu­ro­logy at the World Fede­ra­tion of Neu­ro­logy

2015 – 2017

Spe­a­ker (elec­ted), Cli­ni­cal Neu­ro­sci­en­ces Neu­ro­wis­sen­schaft­li­che Gesell­schaft (Ger­man Society of Neu­ro­sci­ence)

2017 – 2021

Deputy Chair and Chair elec­ted Neu­ro­wis­sen­schaft­li­che Gesell­schaft (Ger­man Society of Neu­ro­sci­ence)

2017 –

Chair Sci­en­ti­fic Advi­sory Board Thierry Lat­ran Founda­tion

Månberg A, Skene N, San­ders F, Tru­so­hamn M, Remnestål J, Szczepińska A, Aksoylu IS, Lön­ner­berg P, Eba­rasi L, Wou­ters S, Leh­mann M, Olofs­son J, von Goh­ren Ante­quera I, Doma­niku A, De Schaep­dry­ver M, De Vocht J, Poe­sen K, Uhlén M, Anink J, Mijns­ber­gen C, Vergunst-​Bosch H, Hübers A, Kläppe U, Rodriguez-​Vieitez E, Gil­thorpe JD, Hed­lund E, Har­ris RA, Aro­nica E, Van Damme P, Ludolph AC, Veld­ink J, Ingre C, Nils­son P, Lewan­dow­ski SA. Alte­red peri­va­s­cu­lar fibro­blast acti­vity pre­ce­des ALS disease onset. Nat Med. 2021 Apr;27(4):640-646.

Dorst J, Schus­ter J, Drey­haupt J, Wit­zel S, Weis­haupt JH, Kas­subek J, Wei­land U, Petri S, Meyer T, Grehl T, Her­mann A, Jor­dan B, Gross­kreutz J, Zel­ler D, Boen­tert M, Schrank B, Prudlo J, Wink­ler AS, Gor­bu­lev S, Roselli F, Dupuis L, Otto M, Ludolph AC. Effect of high-​caloric nutri­tion on serum neu­ro­fi­la­ment light chain levels in amyo­tro­phic late­ral scle­ro­sis. J Neu­rol Neu­ro­surg Psych 2020;91(9):1007-1009

Hagen­acker T, Wurs­ter CD, Gün­ther R, Schreiber-​Katz O, Osma­no­vic A, Petri S, Wei­ler M, Zieg­ler A, Kuttler J, Koch JC, Schnei­der I, Wun­der­lich G, Schloss N, Leh­mann HC, Cordts I, Deschauer M, Lin­gor P, Kamm C, Stolte B, Pie­t­ruck L, Tot­zeck A, Kizina K, Mön­ning­hoff C, von Vel­sen O, Ose C, Reich­mann H, Forsting M, Pech­mann A, Kirsch­ner J, Ludolph AC, Her­mann A, Klein­schnitz C. Nusi­ner­sen in adults with 5q spi­nal mus­cu­lar atro­phy: a non-​interventional, mul­ti­centre, obser­va­tio­nal cohort study. Lan­cet Neu­rol 2020;19(4):317-325

Ludolph AC, Dorst J, Drey­haupt J, Weis­haupt JH, Kas­subek J, Wei­land U, Meyer T, Petri S, Her­mann A, Emmer A, Gross­kreutz J, Grehl T, Zel­ler D, Boen­tert M, Schrank B, Prudlo J, Wink­ler AS, Gor­bu­lev S, Roselli F, Schus­ter J, Dupuis L; LIPCAL-​ALS Study Group. Effect of High-​Caloric Nutri­tion on Sur­vi­val in Amyo­tro­phic Late­ral Scle­ro­sis. Ann Neu­rol 2020;87(2):206-216

Ludolph AC, Emi­lian S, Drey­haupt J, Rosen­bohm A, Kras­kov A, Lemon RN, Del Tre­dici K, Braak H. Pat­tern of pare­sis in ALS is con­sis­tent with the phy­sio­logy of the cor­ti­co­mo­to­neu­ro­nal pro­jec­tions to dif­fe­rent mus­cle groups. J Neu­rol Neu­ro­surg Psych 2020;(9):991-998

Lulé DE, Mül­ler HP, Finsel J, Weydt P, Knehr A, Win­roth I, Ander­sen P, Weis­haupt J, Utt­ner I, Kas­subek J, Ludolph AC. Defi­cits in ver­bal fluency in pre­sym­pto­ma­tic C9orf72 muta­tion gene carriers-​a deve­lo­p­men­tal dis­or­der. J Neu­rol Neu­ro­surg Psych 2020;91(11):1195-1200

Mil­ler T, Cud­ko­wicz M, Shaw PJ, Ander­sen PM, Atassi N, Bucelli RC, Genge A, Glass J, Ladha S, Ludolph AC, Mara­ga­kis NJ, McDer­mott CJ, Pes­tronk A, Ravits J, Salachas F, Tru­dell R, Van Damme P, Zin­man L, Ben­nett CF, Lane R, San­d­rock A, Runz H, Gra­ham D, Hous­hyar H, McCamp­bell A, Nes­torov I, Chang I, McNeill M, Fan­ning L, Fra­dette S, Fer­gu­son TA. Phase 1-2 Trial of Anti­sense Oli­go­nucleo­tide Tofersen for SOD1 ALS. N Engl J Med 2020;383(2):109-119

Oeckl P, Weydt P, Thal DR, Weis­haupt JH, Ludolph AC, Otto M. Pro­teo­mics in cere­bro­s­pi­nal fluid and spi­nal cord sug­gests UCHL1, MAP2 and GPNMB as bio­mar­kers and under­pins impor­tance of tran­scrip­tio­nal pathways in amyo­tro­phic late­ral scle­ro­sis. Acta Neu­ro­pa­thol 2020;139(1):119-134

Ludolph AC, Schus­ter J, Dorst J, Dupuis L, Drey­haupt J, Weis­haupt JH, Kas­subek J, Wei­land U, Petri S, Meyer T, Gross­kreutz J, Schrank B, Boen­tert M, Emmer A, Her­mann A, Zel­ler D, Prudlo J, Wink­ler AS, Grehl T, Heneka MT, Wollebæk Johan­nesen S, Göri­cke B; RAS-​ALS Study Group. Safety and effi­cacy of rasa­gi­line as an add-​on the­rapy to rilu­zole in pati­ents with amyo­tro­phic late­ral scle­ro­sis: a ran­do­mi­sed, double-​blind, parallel-​group, placebo-​controlled, phase 2 trial. Lan­cet Neu­rol 2018;17(8):681-688

Lulé DE, Aho-​Özhan HEA, Vázquez C, Wei­land U, Weis­haupt JH, Otto M, Anderl-​Straub S, Sem­ler E, Utt­ner I, Ludolph AC. Story of the ALS-​FTD con­ti­nuum retold: rather two dis­tinct enti­ties. J Neu­rol Neu­ro­surg Psych 2019;90(5):586-589