Dr. rer. nat. Dipl.-Psych. Michael Fritz
Stellvertretender therapeutischer Direktor
Leitung Sektion Molekulare Genetik und forensische Verhaltenswissenschaften
E-Mail michael.fritz@bkh-guenzburg.de
Werdegang
2000 - 2008 | Magisterstudium Psychologie Leopold-Franzens Universität Innsbruck |
2001 - 2003 | Bakkalaureats Studium Philosophie Leopold-Franzens Universität Innsbruck |
2003 - 2004 | Magisterstudium Philosophie Leopold-Franzens Universität Innsbruck |
2008 - 2010 | Studium zum Doktor der Psychologie (Dr. rer. nat.) an der Abteilung für Experimentelle Psychiatrie der Medizinischen Universität Innsbruck unter Anleitung von Herrn ao. Univ.-Professor Dr. med. univ. Gerald Zernig |
2010 | Promotion (mit Auszeichnung) über das Thema „Cocaine relapse prevention by social interaction and sigma 1 receptor inactivation: Development of an animal model“ |
2010 - 2014 | Wissenschaftlicher Mitarbeiter am Institut für Klinische und Experimentelle Medizin der Universität Linköping, Schweden (Labor von Herrn Univ. Professor David Engblom). Mitarbeit an den Projekten „Circuits and mechanisms behind sickness-induced aversion and depressive symptoms“ und „Inflammation-induced aversion: Brain Circuitry and Molecular Mechanisms“ |
2014 - 2020 | Assistenz (Junior) Professor am Zentrum für Soziale und Affektive Neurowissenschaften der Universität Linköping (Zentrumleitung Univ. Professor DDr. Markus Heilig). Leitung von Forschungsprojekten über Sigma 2 und Acetylcholin Rezeptoren als molekulare Ziele zur Behandlung von Kokainabhängigkeit. |
2016 - 2017 | 3monatiger Aufenthalt als Gastwissenschaftler am Nationalen Institut für Drogensucht (NIDA) und dem Johns Hopkins Krankenhaus, Baltimore, USA im Labor von Dr. Michael Michaelides |
2018 - 2020 | Gastlektor am Institut für Psychiatrie und Verhaltenswissenschaften, Stanford School of Medicine, Stanford Universität, USA |
2020 - 2022 | Wissenschaftlicher Mitarbeiter am Lehrstuhl für Forensische Psychiatrie und Psychotherapie der Universität Ulm, Prof. Manuela Dudeck und Stationspsychologe an der Klinik für Forensische Psychiatrie und Psychotherapie am BKH Günzburg |
2021 - 2022 | Dozent an der IU Internationale Hochschule für die Kurse Allgemeine Psychologie I, Biopsychologie: neurobiologische Grundlagen der Psychologie und Klinische Psychologie Störungslehre |
2021 - 2024 | Ausbildung zum Fachpsychologen für Rechtspsychologie |
2022 - 2024 | Professor für Psychologie und Studiengangleiter für den Bachelorstudiengang Psychologie an der AKAD Hochschule Stuttgart |
2021 - | Leitung der Sektion für Molekulare Genetik und Forensische Verhaltenswissenschaften am Lehrstuhl für Forensische Psychiatrie und Psychotherapie der Universität Ulm, Prof. Manuela Dudeck |
2024 - | Stellvertretender therapeutischer Direktor der Klinik für Forensische Psychiatrie und Psychotherapie der Universität Ulm am BKH Günzburg |
Publikationen
Wissenschaftliche Artikel
Wissenschaftliche Artikel (Präklinik)
Fritz M, El Rawas R, Salti A, Klement S, Bardo MT, Kemmler G, Dechant G, Saria A, Zernig G.Reversal of cocaine-conditioned place preference and mesocorticolimbic Zif268 expression by social interaction in rats. Addict Biol. 2011, 16(2):273-84. doi: 10.1111/j.1369-1600.2010.00285.x.
Fritz M, Klement S, El Rawas R, Saria A, Zernig G. Sigma1 receptor antagonist BD1047 enhances reversal of conditioned place preference from cocaine to social interaction.
Pharmacology. 2011, 87(1-2):45-8. doi: 10.1159/000322534.
Fritz M, El Rawas R, Klement S, Kummer K, Mayr MJ, Eggart V, Salti A, Bardo MT, Saria A, Zernig G. Differential effects of accumbens core vs. shell lesions in a rat concurrent conditioned place preference paradigm for cocaine vs. social interaction.PLoS One. 2011, 6(10):e26761. doi: 10.1371/journal.pone.0026761.
El Rawas R, Klement S, Kummer KK, Fritz M, Dechant G, Saria A, Zernig G. Brain regions associated with the acquisition of conditioned place preference for cocaine vs. social interaction. Front Behav Neurosci. 2012, 6:63. doi: 10.3389/fnbeh.2012.00063.
El Rawas R, Klement S, Salti A, Fritz M, Dechant G, Saria A, Zernig G. Preventive role of social interaction for cocaine conditioned place preference: correlation with FosB/DeltaFosB and pCREB expression in rat mesocorticolimbic areas. Front Behav Neurosci. 2012, 2;6:8. doi: 10.3389/fnbeh.2012.00008.
Fritz M, Klawonn AM, Nilsson A, Singh AK, Zajdel J, Wilhelms DB, Lazarus M, Löfberg A, Jaarola M, Kugelberg UÖ, Billiar TR, Hackam DJ, Sodhi CP, Breyer MD, Jakobsson J, Schwaninger M, Schütz G, Parkitna JR, Saper CB, Blomqvist A, Engblom D. Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice. J Clin Invest. 2016, 126(2):695-705. doi: 10.1172/JCI83844.
Singh AK, Zajdel J, Mirrasekhian E, Almoosawi N, Frisch I, Klawonn AM, Jaarola M, Fritz M, Engblom D. Prostaglandin-mediated inhibition of serotonin signaling controls the affective component of inflammatory pain. J Clin Invest. 2017, 3;127(4):1370-1374. doi: 10.1172/JCI90678.
Klawonn AM, Nilsson A, Rådberg CF, Lindström SH, Ericson M, Granseth B, Engblom D, Fritz M. The Sigma-2 Receptor Selective Agonist Siramesine (Lu 28-179) Decreases Cocaine-Reinforced Pavlovian Learning and Alters Glutamatergic and Dopaminergic Input to the Striatum. Front Pharmacol. 2017, 8:714. doi: 10.3389/fphar.2017.00714.
Fritz M, Klawonn AM, Jaarola M, Engblom D. Interferon-ɣ mediated signaling in the brain endothelium is critical for inflammation-induced aversion. Brain Behav Immun. 2018, 67:54-58. doi: 10.1016/j.bbi.2017.08.020.
Klawonn AM, Wilhelms DB, Lindström SH, Singh AK, Jaarola M, Wess J, Fritz M1, Engblom1 D. Muscarinic M4 Receptors on Cholinergic and Dopamine D1 Receptor-Expressing Neurons Have Opposing Functionality for Positive Reinforcement and Influence Impulsivity. Front Mol Neurosci. 2018, 11:139. doi: 10.3389/fnmol.2018.00139.
Klawonn AM1, Fritz M1, Nilsson A, Bonaventura J, Shionoya K, Mirrasekhian E, Karlsson U, Jaarola M, Granseth B, Blomqvist A, Michaelides M, Engblom D. Motivational valence is determined by striatal melanocortin 4 receptors. J Clin Invest. 2018, 128(7):3160-3170. doi: 10.1172/JCI97854.
Zhao Q, Fritz M, Pfefferbaum A, Sullivan EV, Pohl KM, Zahr NM. Jacobian Maps Reveal Under-reported Brain Regions Sensitive to Extreme Binge Ethanol Intoxication in the Rat. Front Neuroanat. 2018, 12:108. doi: 10.3389/fnana.2018.00108.
Fritz M, Klawonn AM, Zhao Q, Sullivan EV, Zahr NM, Pfefferbaum A. Structural and biochemical imaging reveals systemic LPS-induced changes in the rat brain. J Neuroimmunol. 2020, 348:577367. doi: 10.1016/j.jneuroim.2020.577367.
Klawonn AM1, Fritz M1, Castany S, Pignatelli M, Canal C, Simil F, Tejeda HA, Levinsson J, Jaarola M, Jakobsson J, Hidalgo J, Heilig M, Bonci A, Engblom D. Microglial activation elicits a negative affective state through prostaglandin-mediated modulation of striatal neurons. Immunity, 2021, 54:1-10 doi.org/10.1016/j.immuni.2020.12.016
Manning C. E., Fritz M., Kauer J. Function of Periaqueductal Gray Synapses in the Ventral Tegmental Area following inflammatory injury. ENeuro, 2022, 1-13, doi.org/10.1523/ENEURO.0324-22.2022
Fritz M, Björk-Wilhelms D, Jaarola M, Ruud J, Englbom D, Klawonn AM. Nicotinic α7 receptors function as auto-receptors in the striatum and mediate cocaine-reinforcement, but not food reward. (in Revision in Frontiers in molecular Neuroscience)
Wissenschaftliche Artikel (Klinik)
Fritz M, Wallner R, Grohs U, Kemmler G, Saria A, Zernig G. Comparable sensitivities of urine cotinine and breath carbon monoxide at follow-up time points of three months or more in a smoking cessation trial. Pharmacology. 2010, 85(4):234-40. doi: 10.1159/000280435
Fritz M, Shenar R, Cardenas-Morales L, Jäger M, Streb J, Dudeck M, Franke I. Aggressive and Disruptive Behavior Among Psychiatric Patients With Major Depressive Disorder, Schizophrenia, or Alcohol Dependency and the Effect of Depression and Self-Esteem on Aggression. Front Psychiatry. 2020, 11:599828. doi: 10.3389/fpsyt.2020.599828.
Fritz M, Rösel F, Dobler H, Streb J, Dudeck M. Childhood trauma, the combination of MAO-A and COMT genetic polymorphisms and the joy of being aggressive in forensic psychiatric patients. Brain Sciences, 2021, 11(1008):1-11 doi.org/10.3390/brainsci11081008
Streb J, Lutz M, Dudeck M, Klein V, Maaß C, Fritz M & Franke I: Are women really different? Comparison of Men and Women in a Sample of Forensic Psychiatric Inpatients. Frontiers in Psychiatry, 2022, doi:10.3389/fpsyt.2022.857468
Mayer J, Vasic N, Wolf V, Steiner I, Klein V, Fritz M, Rothe P, Streb J & Dudeck M, Gender Differences in the Pharmacological Treatment of Forensic In-Patients With Schizophrenia. Frontiers in Psychiatry, 2022, doi:10.3389/fpsyt.2022.907123
Fritz M, Karanassios G, Wolf V, Mayer J, Steiner I, Franke I, Klein V, Streb J, Dudeck M, The curse of experiencing and committing violence as a criminal recidivism predictor: a comparison between female forensic psychiatric patients with severe mental disorders and substance use disorder. European Psychiatry, 2023, 66(1):1-6 doi.org/10.1192/j.eurpsy.2023.2450
Soravia S-M, Gosemärker A-K, Streb J, Dudeck M, Fritz M, Does gender-specific suicidal symptomatology exist? Initial work on a partially-novel, multi-questionnaire-based characterization of acute suicidal patients. Cogent Psychology, 2024, 11(1):1-8 DOI: 10.1080/23311908.2024.2328911
Pichlmeier S, Streb J, Rösel F-A, Dobler H, Dudeck M, Fritz M, Subjective and Objective Assessments of Executive Functions are Independently Predictive of Aggressive Tendencies in patients with substance use disorder. Comprehensive Psychiatry, 2024, 132:1-8 DOI: 10.1016/j.comppsych.2024.152475
Fritz M, Montiel F, Al Dirany A, Dudeck M, Streb J, Unravelling Relapse in Male Forensic Psychiatric Patients with Substance Use Disorders – The Impact of Social, Psychiatric, and Personality Factors Post Long-term Remission. International Journal of Mental Health and Addiction, 2024, 1-16 doi.org/10.1007/s11469-024-01333-w
Fritz M, Montiel F, Karanassios G, Dudeck M, Streb J, The relationship between Serum Cholesterol, Triglycerides and self-reported Appetitive and Reactive Aggression, as well as Violent Crimes in Male Forensic Patients with Substance Use Disorder (in Revision in mdpi Psychiatry International)
Review Artikel
Fritz M, Klawonn AM, Zahr NM; Neuroimaging in alcohol use disorder: From mouse to man.
J Neurosci Res. 2019, doi: 10.1002/jnr.24423
Lutz M, Zani D, Fritz M, Dudeck M, Franke I, A Review and Comparative Analysis of the Risk-Needs-Responsivity, Good Lives, and Recovery Models in Forensic Psychiatric Treatment. Frontiers in Psychiatry, 2022, 1-12, doi.org/10.3389/fpsyt.2022.988905
Fritz M, Moravia S.-M., Dudeck M, Fakhoury M. Neurobiology of Aggression – Review of Recent Findings and Relationship with Alcohol and Trauma. MDPI Biology, 2023, 12(3):469. doi.org/10.3390/biology12030469
Editorials
Fakhoury, M. & Fritz, M. Neurobiology of Behavior – Influences of Neuropsychiatric Disorders on Neurobiology and Behavior. MDPI Biology 2023 12(6):807. doi.org/10.3390/biology12060807
Buchkapitel
Klawonn AM, Fritz M. Immune-to-Brain Signaling Effects on the Neural Substrate for Reward: Behavioral Models of Aversion, Anhedonia, and Despair. Neuromethods, 2021, 165, pp. 145–167
Fritz M, Dudeck M. Die Neurobiologie der Delinquenz. Praxishandbuch Forensische Psychiatrie 2022, 3 Auflage
Fakhoury M, Fritz M, Sleiman SF. Behavioral paradigms for assessing cognitive functions in the chronic social defeat stress model of depression. Translational Research Methods for Major Depressive Disorder, 2022, pp. 147-164
Lernmittel
Bender B, Fritz M, PSY271 Grundlagen der Sozialpsychologie (Studienbrief), AKAD-University of applied Sciences, 2023, 1-87, Kennnummer: N2023
Wittling C, Fritz M, PSY281 Einführung in die Psychologische Diagnostik (Studienbrief), AKAD-University of applied Sciences, 2023, 1-99, Kennnummer: N2122
Wittling C, Fritz M, PSY332 Überblicke über die Persönlichkeit (Studienbrief), AKAD-University of applied Sciences, 2023, 1-90, Kennnummer: N2113
Fritz M, Wittling C, PSY921 Grundlagen der Biologischen Psychologie (Studienbrief), AKAD-University of applied Sciences, 2024, 1-93, Kennnummer: N2074
1Diese Autoren teilen die Erst- bzw. Letzt-Autorenschaft.